Mentored Rennica Huang in undergraduate research on GPCR allosteric modulators
As of 2020 · Last known relationship
Seungkirl Ahn is a Duke University cardiology faculty member whose work explores how G protein-coupled receptors and β-arrestins regulate cardiovascular signaling and how these mechanisms can be therapeutically modulated. Duke lists Ahn as an Associate Professor in Medicine; Ahn earned a Ph.D. from Duke in 2002 and previously held an Assistant Professor in Medicine appointment. His research includes molecular regulation of cardiovascular 7 TM receptors and β-arrestins and G protein-coupled receptor kinases in cardiovascular function. Recent publications address small-molecule modulation of β-arrestins, cryo-electron-microscopy-based mechanisms of β-arrestin 1 activation of Src, and allosteric modulators of β-adrenergic receptors. Ahn has also mentored undergraduate research on GPCR allosteric modulators.
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Training includes Ph.D. from Duke University, Mentored Rennica Huang in undergraduate research on GPCR allosteric modulators, Associate Professor in Medicine at Duke University, and Previously held an Assistant Professor in Medicine appointment.
Explore education and trainingGrant on b-arrestins and G protein-coupled receptor kinases in cardiovascular function[10]
2002 to 2012
Grant on molecular regulation of cardiovascular 7 TM receptors[10]
1976 to 2027
Publication: Abstract P2154: A Novel Allosteric Modulator Of The β 1 AR Identified By DNA-encoded Small Molecule Library Screening Demonstrates Unique Pharmacology And Function[10]
From 2023
Publication: Allosteric modulator potentiates β2AR agonist-promoted bronchoprotection in asthma models[10]
From 2023
Publication: A positive allosteric modulator of the β1AR with antagonist activity for catecholaminergic polymorphic ventricular tachycardia[10]
From 2025
Publication: How carvedilol does not activate β2-adrenoceptors[10]
From 2023
Publication: Mechanism of beta-arrestin 1 mediated Src activation via Src SH3 domain revealed by cryo-electron microscopy[10]
From 2026
Publication: Signal transduction at GPCRs: Allosteric activation of the ERK MAPK by β-arrestin[10]
From 2023
Publication: Small-molecule modulation of β-arrestins[10]
From 2026
Publication: Targeting the host factor HGS-viral membrane protein interaction in coronavirus infection[10]
From 2026