Research interests
CPET[4]
Alison S. Witkin
About
Witkin's fellowship profile describes clinical and research interests in pulmonary hypertension and acute and chronic thromboembolic disease. It lists her as associate director of the MGH Pulmonary Hypertension and Thromboendarterectomy Program and director of the medical ICU ECMO program. Listed projects examine CTEPH pathology and hemodynamic outcomes, and cardiopulmonary exercise testing in pulmonary hypertension and persistent symptoms after pulmonary embolism.
Research interests
CPET · CTEPH · ECMO · Pulmonary embolism
Journey
Education, training and research through time.
Medical school
Jefferson Medical College
Residency
Hospital of the University of Pennsylvania
Fellowship
Massachusetts General Hospital
- Completed 2010
- Completed 2013Residency
Residency[5]
Hospital of the University of Pennsylvania
Hospital of the University of Pennsylvania
- Completed 2016
- 2016
1 attributed work
- Pulmonary Embolism Response Teams
Seminars in thrombosis and hemostasis · First author
- Pulmonary Embolism Response Teams
- 2024
- 2025
- Appointment dates not documentedMilestone
Documented faculty and education roles[4][6]
Massachusetts General Hospital; MGH–BIDMC pulmonary and critical care fellowship; Harvard Medical School
Associate Program Director; Massachusetts General Hospital; Associate Program Director; Assistant Professor of Medicine; Associate Director, MGH Pulmonary Hypertension and Thromboendarterectomy Program; Pulmonary and critical care faculty
Works appear by publication year. Their position does not establish where or when the underlying research was performed.
Education and training
Degrees, training periods and the milestones within them.
- Completed 2010
- Completed 2013Residency
Residency[5]
Hospital of the University of Pennsylvania
Hospital of the University of Pennsylvania
- Completed 2016
Research
Resources
Projects and appearances
The PERT Consortium lists Witkin among five course directors for its 11th annual symposium.
Course director
Limitations
- A leadership listing does not establish the content of an individual lecture.
- The retained page does not state an event year in its body; the 2025 URL segment is cycle context only.
Right Ventricular Dysfunction May Prove to Be Common with COVID-19
research story · 2020-06-05An MGH written evidence update summarizes Witkin’s review of right-ventricular dysfunction in critical illness and COVID-19.
Named contributor
Findings
- The article discusses echocardiography, bedside ultrasound, examination, ECG and hemodynamics as complementary assessment tools.
- It distinguishes plausible physiology from then-limited COVID-19 evidence.
Limitations
- The article reflects the 2020 evidence base and is not an original clinical study or current clinical guideline.
Studies Work to Improve Pulmonary Hypertension and HHT Care
research story · 2021-05-17An MGH research story describes pulmonary vascular research and multidisciplinary CTEPH care.
Quoted contributor
Findings
- Witkin describes routine multidisciplinary review of CTEPH referrals and individualized treatment planning.
- The story identifies a local outcomes registry, participation in an international balloon angioplasty registry, and research for nonsurgical or residual CTEPH.
Limitations
- These are institutional descriptions from 2021, not a comparative study of program outcomes or confirmation that trials remain open.
Selected reading
Association Between Thrombus Histopathology and Hemodynamic Outcomes Among Patients With Chronic Thromboembolic Pulmonary Hypertension Undergoing Pulmonary Endarterectomy
Single-center retrospective cohort
Retrospectively classified resected thrombi from 163 endarterectomy patients and modeled postoperative hemodynamics and residual pulmonary hypertension.
Methods
- Retrospectively classified resected thrombi from 163 endarterectomy patients and modeled postoperative hemodynamics and residual pulmonary hypertension.
Findings
- Among 163 surgical patients, mixed organizing and organized thrombus was associated with lower adjusted odds of residual pulmonary hypertension and a larger postoperative pressure reduction than organized thrombus alone.
Limitations
- Histopathology is available after surgery, so the result is not yet a preoperative selection rule.
- Retrospective association cannot show that timing based on thrombus stage improves outcomes.
Pulmonary Embolism Response Teams
Clinical review
Narrative review of the multidisciplinary pulmonary embolism response-team care model.
Methods
- Narrative review of the multidisciplinary pulmonary embolism response-team care model.
Findings
- The review describes a multidisciplinary response-team model for rapid coordination of care in intermediate- and high-risk pulmonary embolism, where anticoagulation, catheter-based treatment, and surgery may be considered.
Limitations
- This is an early review of a care model, not evidence that a PERT structure or any specific intervention improves patient outcomes.
- This 2016 review does not establish current protocols.
Venovenous Extracorporeal Membrane Oxygenation Candidacy Decision-Making: Lessons and Hypotheses From a Single-Center Observational Analysis
Prospective observational study
Prospectively reviewed all 81 VV-ECMO consultations at one tertiary referral center and compared documented contraindications across candidate decisions.
Methods
- Prospectively reviewed all 81 VV-ECMO consultations at one tertiary referral center and compared documented contraindications across candidate decisions.
Findings
- Across 81 VV-ECMO consultations, 44 people were judged noncandidates, 29 candidates, and eight decisions were deferred.
- Fifteen contraindications were used inconsistently: 26 of 29 candidates had at least one feature that had been prohibitive in a noncandidate, and contraindications documented in some noncandidates were present but unmentioned in 21 others.
Limitations
- This was one tertiary referral center.
- Comparing recorded rationales can expose inconsistency but cannot determine that every different decision was wrong, establish causal bias, or show which standardization strategy improves patient outcomes; only nine candidates were cannulated.
Publications
3 attributed works · 1 first author. Counts reflect resolved authorship and may be incomplete.
- 2016Pulmonary Embolism Response TeamsSeminars in thrombosis and hemostasisfirst authorPMID 27769084
Sources
Sources are listed once and connected to each accepted claim they support. Excerpts preserve the source language used in the review.
- [1]Association Between Thrombus Histopathology and Hemodynamic Outcomes Among Patients With Chronic Thromboembolic Pulmonary Hypertension Undergoing Pulmonary Endarterectomy
1 source claim · Reviewed Sep 9, 2026
Attributed work: Association Between Thrombus Histopathology and Hemodynamic Outcomes Among Patients With Chronic Thromboembolic Pulmonary Hypertension Undergoing Pulmonary Endarterectomy | DOI 10.1016/j.chest.2024.10.018 | PMID 39454997 | 2025
2025
responseWrapper/resultList/result/authorList; own id and doi; matched byline Alison S Witkin
- [2]Pulmonary Embolism Response Teams
1 source claim · Reviewed Sep 9, 2026
Attributed work: Pulmonary Embolism Response Teams | DOI 10.1055/s-0036-1593541 | PMID 27769084 | 2016
2016
resultList.result[0].authorList; own id and doi; matched byline Alison S Witkin
- [3]Venovenous Extracorporeal Membrane Oxygenation Candidacy Decision-Making: Lessons and Hypotheses From a Single-Center Observational Analysis
2 source claims · Reviewed Sep 9, 2026
Attributed work: Venovenous Extracorporeal Membrane Oxygenation Candidacy Decision-Making: Lessons and Hypotheses From a Single-Center Observational Analysis | DOI 10.1016/j.chest.2024.02.042 | PMID 38423278 | 2024
2024
PubmedArticle[MedlineCitation/PMID='38423278']/MedlineCitation/Article/AuthorList; matched byline Alison S Witkin
Article title and named author/affiliation block: Venovenous ECMO Candidacy Decision-Making: Lessons and Hypotheses From a Single-Center Observational Analysis Retained normalized text /Users/tejas/.local/share/medcorpus/research/shared-person-knowledge-2026-09-08/mgh/derived/src-a20b2e4b5a9560ad.txt; candidate evidence lines 1-1.
- [4]https://www.pulmonaryfellowship.hms.harvard.edu/alison-witkin-md
9 source claims · 2 journey details · Reviewed Sep 9, 2026
Documented faculty and education roles: Appointment dates not documented. Associate Program Director; Massachusetts General Hospital; Associate Program Director; Assistant Professor of Medicine; Associate Director, MGH Pulmonary Hypertension and Thromboendarterectomy Program; Pulmonary and critical care faculty
Appointment dates that are not stated in the sources remain unknown. Education completion dates mark completion only; they do not establish attendance periods.
Biographical context: Witkin's fellowship profile describes clinical and research interests in pulmonary hypertension and acute and chronic thromboembolic disease. It lists her as associate director of the MGH Pulmonary Hypertension and Thromboendarterectomy Program and director of the medical ICU ECMO program. Listed projects examine CTEPH pathology and hemodynamic outcomes, and cardiopulmonary exercise testing in pulmonary hypertension and persistent symptoms after pulmonary embolism.
Named person profile, Academic Interests and Current Projects; each sentence limited to this source. Undated project descriptions do not establish current enrollment or personal mentorship availability.
Official headshot: Portrait
Image attached to named official Alison S. Witkin profile/card; original source URL https://images.squarespace-cdn.com/content/v1/5989e512d2b8578f99509325/1561941670958-0FODNDPGAK54O0CH05LC/witkin.jpg Retained normalized text /Users/tejas/.local/share/medcorpus/research/shared-person-knowledge-2026-09-08/mgh/derived/src-0ba3ae1883704d5f.txt; candidate evidence lines 50-52, 47-49, 42-44.
Professional role: Assistant Professor of Medicine
Named person role heading or biography; source-specific role: Assistant Professor of Medicine. Currentness requires independent source-date review.
Professional role: Associate Director, MGH Pulmonary Hypertension and Thromboendarterectomy Program
Named person role heading or biography; source-specific role: Associate Director, MGH Pulmonary Hypertension and Thromboendarterectomy Program. Currentness requires independent source-date review.
Professional role: Associate Program Director
Named person role heading or biography; source-specific role: Associate Program Director. Currentness requires independent source-date review.
Research interests: CPET
Named person profile Academic Interests or Current Projects; topic term(s): CPET
Research interests: CTEPH
Named person profile Academic Interests or Current Projects; topic term(s): CTEPH
Research interests: ECMO
Named person profile Academic Interests or Current Projects; topic term(s): ECMO
Research interests: Pulmonary embolism
Named person profile Academic Interests or Current Projects; topic term(s): Pulmonary embolism
- [5]https://doctors.massgeneralbrigham.org/provider/alison-s-witkin/3002494
3 source claims · 4 journey details · Reviewed Sep 9, 2026
Medical education: Completed 2010. Jefferson Medical College
Residency: Completed 2013. Hospital of the University of Pennsylvania
Fellowship: Completed 2016. Massachusetts General Hospital
Appointment dates that are not stated in the sources remain unknown. Education completion dates mark completion only; they do not establish attendance periods.
Education record: Jefferson Medical College
Named person education/training section; institution reported as Jefferson Medical College. Reviewer must verify the stated training stage in this source; no dates inferred from adjacent episodes.
Fellowship: Massachusetts General Hospital
Named provider profile Education section, explicitly labeled Fellowship or Residency row. Retained normalized source text: /Users/tejas/.local/share/medcorpus/research/shared-person-knowledge-2026-09-08/mgh/derived/src-c15fd222b002d60f.txt. Source-local assertion: Massachusetts General Hospital
Residency: Hospital of the University of Pennsylvania
Named person education/training section; institution reported as Hospital of the University of Pennsylvania. Reviewer must verify the stated training stage in this source; no dates inferred from adjacent episodes.
- [6]https://www.pulmonaryfellowship.hms.harvard.edu/faculty
2 source claims · 2 journey details · Reviewed Sep 9, 2026
Documented faculty and education roles: Appointment dates not documented. Associate Program Director; Massachusetts General Hospital; Associate Program Director; Assistant Professor of Medicine; Associate Director, MGH Pulmonary Hypertension and Thromboendarterectomy Program; Pulmonary and critical care faculty
Appointment dates that are not stated in the sources remain unknown. Education completion dates mark completion only; they do not establish attendance periods.
Professional role: Associate Program Director; Massachusetts General Hospital
Named roster card for Alison Witkin; preserve source cohort label rather than infer current year. Retained normalized text /Users/tejas/.local/share/medcorpus/research/shared-person-knowledge-2026-09-08/mgh/derived/src-c88a0638f794cc0e.txt; candidate evidence lines 345-347, 344-346, 125-127.
Professional role: Pulmonary and critical care faculty
Named person role heading or biography; source-specific role: Pulmonary and critical care faculty. Currentness requires independent source-date review.
