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Alex George

Pediatrics / Pediatric Hematology-Oncology

Credentials: · · · · ·

History

Pediatrics
Cincinnati Children's Hospital Medical Center
2007–2010
Baylor College of Medicine
2001–2005

Research

Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to…
The Lancet · 2016 · 384 citations
Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease
Blood · 2013 · First of 9 authors · Corresponding · 170 citations
Altered phosphorylation of cytoskeleton proteins in sickle red blood cells: the role of protein kinase C, Rac GTPases, and reactive oxygen species
Review · Blood cells · 2010 · First of 8 authors · 54 citations

Theodosia Kalfa
6 papers
Ofelia Alvarez
4 papers
Beng Fuh
3 papers
CJ
Clinton Joiner
3 papers
Connie Piccone
3 papers
JK
Julie Kanter
3 papers
Matthew Heeney
3 papers
Russell Ware
3 papers
Alexis Thompson
2 papers
AR
Ashok Raj
2 papers
Banu Aygun
2 papers
Carla Roberts
2 papers

Clinical trials

Novel Dose Escalation to Predict Treatment With Hydroxyurea
Principal investigator · Completed · Early phase 1
Baylor College of Medicine
2013–2020
A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)
Site PI · Recruiting · Phase 3
Novartis Pharmaceuticals
2024–2030