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Amy Clark

Associate Director for Clinical Research · University of Pennsylvania Health System

Credentials: · · · ·

History

University of Pennsylvania Health System
Present
Perelman School of Medicine at the University of Pennsylvania
Present
University of Pennsylvania Health System
Present

University of Pennsylvania Health System
2009–2011
Internal Medicine
Boston Medical Center
2006–2009
Penn State College of Medicine
2002–2006

Research

Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation
Cancer Research · 2001 · 801 citations
Effect of Pembrolizumab Plus Neoadjuvant Chemotherapy on Pathologic Complete Response in Women With Early-Stage Breast Cancer: An Analysis of the Ongoing Phase 2 Adaptively…
JAMA Oncology · 2020 · 610 citations
Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells
Molecular Cancer Therapeutics · 2002 · First of 4 authors · 538 citations

Angela DeMichele
40 papers
Laura Esserman
20 papers
Rita Nanda
19 papers
Claudine Isaacs
18 papers
Hope Rugo
18 papers
Douglas Yee
17 papers
Judy Boughey
16 papers · 1 as a fellow
Anne Wallace
15 papers
Anthony Elias
15 papers
Jo Chien
15 papers
Kathy Albain
15 papers
William Symmans
15 papers

Grants

Abramson Cancer Center Support Grant
National Cancer Institute · P30
Project lead · $1.5M · University of Pennsylvania
1997–2027

Clinical trials

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
Site PI · Recruiting · Phase 2
QuantumLeap Healthcare Collaborative
2010–2031