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Arlene Siefker-Radtke

Professor · University of Texas M D Anderson Cancer Center

Credentials: · ·

History

University of Texas M D Anderson Cancer Center
Present

University of Texas M D Anderson Cancer Center
1999–2002
Internal Medicine
Tufts Medical Center
1996–1999
Johns Hopkins Univ Sch of Med
1992–1996

Research

Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy
Cancer Cell · 2014 · 1,404 citations
Nivolumab in metastatic urothelial carcinoma after platinum therapy (CheckMate 275): a multicentre, single-arm, phase 2 trial
The Lancet Oncology · 2017 · 1,336 citations
Erdafitinib in Locally Advanced or Metastatic Urothelial Carcinoma
New England Journal of Medicine · 2019 · 1,067 citations

Colin Dinney
53 papers
Ashish Kamat
44 papers
Charles Guo
33 papers
Jianjun Gao
33 papers
Bogdan Czerniak
31 papers
Matthew Campbell
27 papers · 3 as a fellow
Amishi Shah
21 papers · 2 as a fellow
Omar Alhalabi
20 papers · 7 as a fellow
Neema Navai
17 papers · 3 as a fellow
Nizar Tannir
17 papers
RM
Randall Millikan
17 papers
HG
Herbert Grossman
16 papers

Grants

Lineage Plasticity Sensitizes FGFR3-Mutant Bladder Cancer to FGFR Inhibitors
National Cancer Institute · R01
PI · $637.5K · University of Tx Md Anderson Can Ctr
2026–2031
SPORE in Genitourinary Cancer
National Cancer Institute · P50
Project lead · $1.1M · University of Tx Md Anderson Can Ctr
2011–2019

Clinical trials

Ixazomib Citrate With Gemcitabine Hydrochloride and Doxorubicin Hydrochloride in Treating Patients With Urothelial Cancer That is Metastatic or Cannot Be Removed by Surgery
Principal investigator · Active not recruiting · Phase 1, Phase 2
M.D. Anderson Cancer Center
2015–2025
A Phase I Study of Systemic Gene Therapy With SGT-94 in Patients With Solid Tumors
Principal investigator · Completed · Phase 1
SynerGene Therapeutics, Inc.
2012–2015
Erlotinib Hydrochloride in Treating Participants With Muscle Invasive or Recurrent Urothelial Cancer
Principal investigator · Completed · Phase 2
M.D. Anderson Cancer Center
2008–2019
Neoadjuvant Chemotherapy With Methotrexate, Vinblastine, Adriamycin and Cisplatin (M-VAC) Plus Avastin in Patients With Urothelial Cancer
Principal investigator · Completed · Phase 2
M.D. Anderson Cancer Center
2007–2014