Brendan Lucey
Professor · University of Minnesota
Credentials: · · · · ·
History
- Present
- 2009–2010
Sleep Medicine
- 2007–2008
Clinical Neurophysiology
- 1999–2003
Research
Sleep and Alzheimer disease pathology--a bidirectional relationship
Review · Nature Reviews Neurology · 2014 · 761 citations
The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans
Science · 2019 · 662 citations
Reduced non-rapid eye movement sleep is associated with tau pathology in early Alzheimer's disease
Science Translational Medicine · 2019 · First of 12 authors · Corresponding · 297 citations
16 papers
16 papers
15 papers
- AS
6 papers
5 papers
5 papers · 2 as a resident
- GH
5 papers
4 papers
Grants
- 2023–2029
Effect of Suvorexant on Alzheimer's Disease Biomarkers
National Institute on Aging · R01
Contact PI · $3.1M · Washington University
- 2026–2027
Breathing Therapy to Improve Clearance of Brain Toxins in Elder Poor Sleepers
National Institute on Aging · R56
PI · $635.3K · University of Miami School of Medicine
- 1997–2026
Healthy Aging and Senile Dementia
National Institute on Aging · P01
Project lead · $1M · Washington University
- 2021–2025
Characterization of Orexin/Hypocretin Kinetics in Alzheimer's Disease
National Institute on Aging · R21
Contact PI · $433.1K · Washington University
Clinical trials
- 2024–2030
DORA and LP in Alzheimer's Disease Biomarkers
Principal investigator · Recruiting · Phase 2
University of Minnesota
- 2023
Acute Effect of Lemborexant on CSF Amyloid-Beta and Tau
Principal investigator · Withdrawn · Phase 2
Brendan Lucey
- 2022–2028
Sleep Trial to Prevent Alzheimer's Disease
Principal investigator · Recruiting · Phase 2
University of Minnesota
- 2016–2021
Sleep Quality and Amyloid-Beta Kinetics
Principal investigator · Completed
Washington University School of Medicine