Brian Appleby
Director, National Prion Disease Pathology Surveillance Center · Case Western Reserve University
Credentials: · · · · ·
History
- Present
National Prion Disease Pathology Surveillance Center · Case Western Reserve University
- 2004–2007
- 1995–1999
Research
The association of neuropsychiatric symptoms in MCI with incident dementia and Alzheimer disease
American Journal of Geriatric Psychiatry · 2013 · 289 citations
Biomarkers and diagnostic guidelines for sporadic Creutzfeldt-Jakob disease
Review · The Lancet Neurology · 2021 · 255 citations
Systematic review or meta-analysis · Movement Disorders · 2007 · First of 4 authors · Corresponding · 175 citations
34 papers
- AB
33 papers
33 papers
33 papers
32 papers
- HR
30 papers
30 papers
29 papers
Grants
- 2021–2031
Cleveland Alzheimer's Disease Research Center
National Institute on Aging · P30
Project lead · $3.3M · Cleveland Clinic Lerner Com-Cwru
Clinical trials
- 2026–2036
PROSPECT Registry for Individuals at Risk for Genetic Prion Disease
Principal investigator · Recruiting
Brian Appleby
- 2026–2029
PrP-targeting siRNA Safety & Mechanism Study
Site PI · Recruiting · Phase 1
Broad Institute of MIT and Harvard