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Cassie Kline

Director, Neuro-Oncology Clinical Research · Children's Hospital of Philadelphia

Credentials: · · ·

History

Neuro-Oncology Clinical Research · Children's Hospital of Philadelphia
Present
Pediatric Neuro-Oncology Consortium · Children's Hospital of Philadelphia
Present
University of California (San Francisco) School of Medicine
Present

MAS Clinical Research University of California
2015–2017
Pediatric Hematology Oncology
University of California-San Francisco
2012–2015
Pediatrics
Children's Hospital of Philadelphia
2011–2014
MD - University of California, San Diego, San Diego, CA.
UC San Diego School of Medicine
2007–2011
University of Virginia, Charlottesville, VA.
2000–2004

Research

Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy
Neuro-Oncology · 2017 · First of 28 authors · 207 citations
The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial
Nature Medicine · 2024 · 168 citations
Clinically Relevant and Minimally Invasive Tumor Surveillance of Pediatric Diffuse Midline Gliomas Using Patient-Derived Liquid Biopsy
Clinical Cancer Research · 2018 · 162 citations

Sabine Mueller
51 papers
Nalin Gupta
18 papers
David Solomon
17 papers
Michael Prados
17 papers
Anuradha Banerjee
16 papers
Joanna Phillips
12 papers
Andrew Bollen
11 papers · 10 as a fellow
Arie Perry
11 papers
CK
Carl Koschmann
10 papers
CR
Corey Raffel
10 papers
Tarik Tihan
10 papers
DS
David Samuel
9 papers

Clinical trials

Tovorafenib for Treatment of Craniopharyngioma in Children and Young Adults
Study chair · Recruiting · Phase 2
Sabine Mueller, MD, PhD
2022–2028
A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)
Site PI · Recruiting · Phase 1, Phase 2
National Cancer Institute (NCI)
2022–2027
Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and Ependymoma
Site PI · Recruiting
University of California, San Francisco
2022–2028
Combination Therapy for the Treatment of Diffuse Midline Gliomas
Site PI · Recruiting · Phase 2
University of California, San Francisco
2021–2029