Christopher DeRenzo
Pediatrics / Pediatric Hematology-Oncology
Credentials: · · · · ·
History
Research
Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity
Science Translational Medicine · 2021 · 309 citations
CAR T Cell Therapy for Solid Tumors: Bright Future or Dark Reality?
Review · Molecular Therapy · 2020 · 308 citations
Case report · Nature Communications · 2020 · 155 citations
27 papers
5 papers
4 papers · 2 as a fellow
2 papers
2 papers
2 papers
2 papers · 2 as a fellow
2 papers
Grants
- 2022–2027
Enhancing B7-H3-CAR T Cell Therapy for Pediatric Solid Tumors
National Cancer Institute · R01
Contact PI · $2.9M · St. Jude Children's Research Hospital
Clinical trials
- 2023–2028
Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors
Principal investigator · Active not recruiting · Phase 1
St. Jude Children's Research Hospital