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Darren Sigal

Physician · OSF HealthCare

Credentials: · · · · ·

History

OSF HealthCare
2026–Present

Hematology and Medical Oncology
Scripps Clinic
2005–2008
Internal Medicine
University of California-Davis
2002–2005
David Geffen Sch of Med at UCLA
1998–2002

Research

Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1-2 trials
The Lancet Oncology · 2020 · 1,363 citations
Randomized Phase III Trial of Pegvorhyaluronidase Alfa With Nab-Paclitaxel Plus Gemcitabine for Patients With Hyaluronan-High Metastatic Pancreatic Adenocarcinoma
Journal of Clinical Oncology · 2020 · 422 citations
HALO 202: Randomized Phase II Study of PEGPH20 Plus Nab-Paclitaxel/Gemcitabine Versus Nab-Paclitaxel/Gemcitabine in Patients With Untreated, Metastatic Pancreatic Ductal…
Journal of Clinical Oncology · 2018 · 407 citations

AS
Alan Saven
9 papers
David Hermel
6 papers · 5 as a fellow
Apostolia Tsimberidou
3 papers
Munveer Bhangoo
3 papers · 3 as a fellow
Nathan Bahary
3 papers
Alyssa Beck
2 papers
Andrea Bullock
2 papers
Andrew Hendifar
2 papers
FB
Fei Bao
2 papers
Heinz-Josef Lenz
2 papers
Howard Hochster
2 papers
James Mason
2 papers

Clinical trials

ABX196 in Combination With Nivolumab in Patients With Hepatocellular Carcinoma
Principal investigator · Recruiting · Phase 1, Phase 2
Abivax S.A.
2019–2023
PEGPH20 Plus Gemcitabine With Radiotherapy in Patients With Localized, Unresectable Pancreatic Cancer
Principal investigator · Terminated · Phase 2
Scripps Health
2017–2018
TH-302 Plus Doxorubicin Delivered by Trans-Arterial Chemoembolization (TACE) in Patients With Hepatocellular Carcinoma
Principal investigator · Unknown · Phase 1
Scripps Clinic Cancer Center
2014–2016