David Smith
Physician · University of Michigan Health-Ann Arbor
Credentials: · · · ·
History
1988–1990- 1985–1988
Internal Medicine
Research
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
New England Journal of Medicine · 2012 · 10,404 citations
Integrative clinical genomics of advanced prostate cancer
Cell · 2015 · 2,800 citations
The Lancet · 2016 · 2,381 citations
32 papers
32 papers
- DT
21 papers
- AA
12 papers
- JM
12 papers
- UV
12 papers
10 papers
10 papers
Grants
- 2006–2011
University of Michigan Rogel Cancer Center Support Grant 2023-2028
National Cancer Institute · P30
Project lead · $1.2M · University of Michigan at Ann Arbor
- 1997–2007
General Clinical Research Center
National Center for Research Resources · M01
Project lead · $149.5K · University of Michigan at Ann Arbor
- 2001–2004
Phase II Trial of Tetrathiomolybdate in Prostate Cancer
National Cancer Institute · R21
Contact PI · $611.6K · University of Michigan at Ann Arbor
- 1995–1998
Phase Ii Clinical Trials of New Chemopreventive Agents
National Cancer Institute · N01
Contact PI · $632.3K · University of Michigan at Ann Arbor
Clinical trials
- 2014–2017
A Phase 1 Study of OMP-305B83 in Subjects With Solid Tumors
Principal investigator · Completed · Phase 1
OncoMed Pharmaceuticals, Inc.
- 2012–2015
Trial of Cabozantinib (XL184) in Castrate-Resistant Prostate Cancer Metastatic to Bone
Principal investigator · Terminated · Phase 2
University of Michigan Rogel Cancer Center
- 2010–2013
A Dose Escalation Study of OMP-59R5 in Subjects With Solid Tumors
Principal investigator · Completed · Phase 1
OncoMed Pharmaceuticals, Inc.
- 2007–2013
Neoadjuvant ABI-007, Carboplatin and Gemcitabine in Locally Advanced Bladder Cancer
Principal investigator · Completed · Phase 2
University of Michigan Rogel Cancer Center