Dennis Selkoe
Co-Director, Ann Romney Center for Neurologic Diseases · Mass General Brigham
Credentials: · · ·
History
- Present
Ann Romney Center for Neurologic Diseases · Mass General Brigham
- Present
- 1972–1976
Neurology
- 1965–1969
Research
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
Review · Science · 2002 · 10,995 citations
Alzheimer's disease: genes, proteins, and therapy
Review · Physiological Reviews · 2001 · Sole author · 4,904 citations
The amyloid hypothesis of Alzheimer's disease at 25 years
Review · EMBO Molecular Medicine · 2016 · First of 2 authors · 4,721 citations
- KK
22 papers
- EK
20 papers
18 papers
18 papers · 5 as a resident
18 papers · 2 as a resident
16 papers · 2 as a resident
- RS
16 papers
14 papers
Grants
- 1998–2025
Presenilin Biology and the Mechanisms of Alzheimer's Disease
National Institute on Aging · P01
Contact PI · $54.1M · Brigham and Women's Hospital
- 2014–2025
Biology of Native Alpha-Synuclein Tetramers in Parkinson's Disease
National Institute of Neurological Disorders and Stroke · RF1
Contact PI · $2.9M · Brigham and Women's Hospital
- 1985–2022
Aging in the Brain: Role of the Fibrous Proteins
National Institute on Aging · RF1
Contact PI · $2.2M · Brigham and Women's Hospital
- 2018–2020
A New Look at Mechanism-Based Alzheimer's Disease Biomarkers in Blood
National Institute on Aging · R21
Contact PI · $492.3K · Brigham and Women's Hospital