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Derek Southwell

Associate Professor of Neurosurgery · Duke University Hospital

Credentials: · · · · · ·

History

Neurological Surgery
University of California (San Francisco) School of Medicine
2013–2018
Stanford University
2011–2013
Neuroscience, University of California, San Francisco
Univ of California, San Francisco Sch of Med
2007–2011

Research

Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development
Cell stem cell · 2013 · 430 citations
Intrinsically determined cell death of developing cortical interneurons
Nature · 2012 · First of 12 authors · Corresponding · 287 citations
Cortical plasticity induced by inhibitory neuron transplantation
Science · 2010 · First of 5 authors · 224 citations

Birgit Frauscher
10 papers
Saurabh Sinha
9 papers · 4 as a resident
Shervin Rahimpour
9 papers · 4 as a fellow
Allan Friedman
7 papers
Shivanand Lad
7 papers · 4 as a resident
JR
John Rubenstein
6 papers
Stephen Harward
6 papers · 3 as a resident
Matthew Vestal
5 papers · 5 as a resident
Mitchel Berger
5 papers
Prachi Parikh
5 papers
Michael Haglund
4 papers · 1 as a resident
Shruti Agashe
4 papers · 4 as a fellow

Grants

Exploring Cortical Inhibitory Circuit Design in the Human Brain
National Institute of Mental Health · DP2
Contact PI · $1.4M · Duke University
2024–2027

Clinical trials

Thalamic Stimulation for Epilepsy Study
Principal investigator · Withdrawn
Duke University
2023–2025
A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)
Site PI · Recruiting · Phase 1, Phase 2
Neurona Therapeutics
2024–2042
Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
Site PI · Recruiting · Phase 3
Neurona Therapeutics
2022–2043