Diva De León-Crutchlow

Chair, Division of Endocrinology Scientific Review Committee · Children's Hospital of Philadelphia

Credentials: · ·

History

Division of Endocrinology Scientific Review Committee Department · Children's Hospital of Philadelphia
Present
Division of Endocrinology/Diabetes · University of Pennsylvania Health System
Present
Congenital Hyperinsulinism Center · Children's Hospital of Philadelphia
Present

Islet Dysregulation in Infants with Congenital Hyperinsulinism
National Institute of Diabetes and Digestive and Kidney Diseases · R01
Contact PI · $4.6M · Children's Hosp of Philadelphia
1999–2025
Insulin Secretion in Hyperinsulinism Human Islets
National Institute of Diabetes and Digestive and Kidney Diseases · R01
Contact PI · $4.5M · Children's Hosp of Philadelphia
2013–2024
Development of Novel Prodrugs Targeting Glutamate Dehydrogenase (GDH) for the Treatment of Congenital Hyperinsulinemia Disorder Including Hyperinsulinemia-Hyperammonemia Syndrome (HHS) and SCHAD-HI.
National Institute of Diabetes and Digestive and Kidney Diseases · R43
PI · $299K · Avanti Biosciences, Inc.
2018–2020
Congenital Hypoglycemia Disorders: Hyperinsulinism and Glycogen Storage Diseases
National Institute of Diabetes and Digestive and Kidney Diseases · R13
Contact PI · $10K · Children's Hosp of Philadelphia
2016–2017

Effect of Exendin-(9-39) on Fasting Adaptation and Protein Sensitivity
Principal investigator · Completed · Phase 1, Phase 2
Diva De Leon
2009–2017