Edmond M. Chan
Assistant Professor of Medicine · Columbia University Irving Medical Center
Credentials: · · · · ·
History
- Present
Columbia University Irving Medical Center
Research
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
Nature · 2009 · 3,074 citations
WRN helicase is a synthetic lethal target in microsatellite unstable cancers
Nature · 2019 · Co-first of 41 authors · 358 citations
Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases
Proceedings of the National Academy of Sciences of the United States of America · 2008 · 274 citations
- AB
3 papers
3 papers
3 papers
2 papers
2 papers · 2 as a fellow
- JP
2 papers
2 papers
- SM
2 papers
Grants
- 2026–2031
National Cancer Institute · R01
Contact PI · $501.4K · Columbia University Health Sciences
- 2021–2026
Advancing WRN as a Synthetic Lethal Target for Microsatellite Unstable Cancers
National Cancer Institute · K08
Contact PI · $1.1M · Columbia University Health Sciences