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Gail Hecht

Chief, Gastroenterology and Nutrition · University of North Carolina Hospitals

Credentials: · ·

History

Gastroenterology and Nutrition Division · University of North Carolina Hospitals
Present
Loyola University Medical Center
Present
University of North Carolina Hospitals
Present

Gastroenterology
Brigham and Women's Hospital
1985–1988
Internal Medicine
1982–1985
Loyola University Chicago Stritch School of Medicine
1978–1982

Research

Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation
Review · Gut · 2003 · Last of 4 authors · 449 citations
Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers
Journal of Clinical Investigation · 1988 · First of 4 authors · 325 citations
A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease
Gastroenterology · 2002 · 307 citations

JT
Jerrold Turner
7 papers
Kristina Matkowskyj
7 papers · 1 as a resident
Jorge Marrero
5 papers
JM
James Madara
4 papers
Amy Lo
3 papers · 2 as a resident
Gary Wu
3 papers · 2 as a resident
John Alverdy
3 papers
Lila Glotfelty
3 papers · 2 as a resident
Michelle Muza-Moons
3 papers
Robert Orenstein
3 papers
Sahil Khanna
3 papers
DG
Dale Gerding
2 papers

Grants

Genetic and Virulence Characterization of Eae-Positive Enteropathogenic E. coli (EPEC) Clinical Isolates from USA Patients with Diarrhea
National Institute of Allergy and Infectious Diseases · R21
Contact PI · $420.3K · Loyola University Chicago
2019–2022
Mechanisms of Cytoskeletal Regulation of Tight Junction Homeostasis and Repair
Department of Veterans Affairs · I01
Contact PI · Edward Hines Jr Va Hospital
2015–2019
Mechanisms of Enteropathogenic E. coli Effects on Polarity and Tight Junctions
National Institute of Diabetes and Digestive and Kidney Diseases · R01
Contact PI · $1.6M · Loyola University Chicago
2012–2018
Molecular Training in Gastroenterology and Hepatology
National Institute of Diabetes and Digestive and Kidney Diseases · T32
Contact PI · $2.1M · University of Illinois at Chicago
2000–2015