Gwendolyn Sowa

Professor and Department Chair · UPMC Medical Education

Credentials: · · · ·

History

UPMC Medical Education
Present
Department of Physical Medicine and Rehabilitation · UPMC Medical Education
Present
Ferguson Laboratory for Orthopaedic Research · Univ of Pittsburgh Sch of Med
Present

Low back pain
Journal of Orthopaedic and Sports Physical Therapy · 2012 · 653 citations
Expression and regulation of metalloproteinases and their inhibitors in intervertebral disc aging and degeneration
Review · The Spine Journal · 2013 · 366 citations
Molecular mechanisms of biological aging in intervertebral discs
Review · Journal of Orthopaedic Research® · 2016 · 310 citations

Whole Person Experience of Pain: Novel Integration with Low Back Pain Phenotypes
National Institute of Arthritis and Musculoskeletal and Skin Diseases · UC2
Contact PI · $6M · University of Pittsburgh at Pittsburgh
2025–2030
Metabolic Symbiosis: Lactate as an Epigenetic Regulator and a Biofuel in Age-Dependent Intervertebral Disc Degeneration
National Institute of Arthritis and Musculoskeletal and Skin Diseases · R01
PI · $1.8M · University of Pittsburgh at Pittsburgh
2022–2027
HEALing LB3P: Profiling Biomechanical, Biological and Behavioral Phenotypes
National Institute of Arthritis and Musculoskeletal and Skin Diseases · U19
Contact PI · $21.7M · University of Pittsburgh at Pittsburgh
2019–2025
Alternative Treatments for Disc Degeneration: Effects on Matrix Homeostasis
National Center for Complementary and Integrative Health · K08
Contact PI · $624.6K · University of Pittsburgh at Pittsburgh
2009–2014

The BEST Trial: Biomarkers for Evaluating Spine Treatments
Principal investigator · Completed · Phase 4
University of North Carolina, Chapel Hill
2022–2024
Effects of Metformin on Low Back Pain
Principal investigator · Terminated · Phase 2
Gwendolyn Sowa
2020–2023
Treatment Validation for Myofascial Pain
Sub-investigator · Recruiting
Ajay Wasan, MD, Msc
2025–2027