Haakon Nygaard
Psychiatry & Neurology / Neurology
Credentials: · · ·
History
2008–2012- 2004–2008
Doctor of Medicine
Research
Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers
Nature · 2009 · 1,291 citations
Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons
Nature Neuroscience · 2012 · 553 citations
Neuron · 2013 · 491 citations
- SS
16 papers
- CD
4 papers
- AV
3 papers
2 papers · 1 as a resident
2 papers
- JV
2 papers
2 papers
2 papers
Grants
- 2013–2018
Fyn Inhibition by AZD0530 for Alzheimers Disease
National Center for Advancing Translational Sciences · UH3
PI · $8.5M · Yale University
- 2013–2014
Fyn Inhibition by AZD0530 for Alzheimers Disease
National Center for Advancing Translational Sciences · UH2
PI · $2.9M · Yale University
Clinical trials
- 2016–2020
A Medium Chain Triglyceride Intervention for Patients With Alzheimer Disease
Principal investigator · Completed
University of British Columbia
- 2013–2014
Safety and Tolerability of AZD0530 (Saracatinib) in Alzheimer's Disease
Principal investigator · Completed · Phase 1
Stephen M. Strittmatter