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Heath Skinner

Chair and Associate Professor, Department of Radiation Oncology · UPMC Medical Education

Credentials: · · · · ·

History

Department of Radiation Oncology · UPMC Medical Education
Present
Radiation Oncology Clinical Networks · UPMC Medical Education
Present
Radiation Oncology Department · UPMC Medical Education
Present

Radiation Oncology
2008–2012
Preliminary or Transitional Year
2007–2008
West Virginia University School of Medicine
2003–2007

Research

TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence
Clinical Cancer Research · 2012 · First of 10 authors · 243 citations
Association of Body Composition With Survival and Locoregional Control of Radiotherapy-Treated Head and Neck Squamous Cell Carcinoma
JAMA Oncology · 2016 · 210 citations
Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation
Molecular Cell · 2014 · 208 citations

Vlad Sandulache
38 papers · 19 as a resident
Jeffrey Myers
34 papers
Jaffer Ajani
28 papers
Adam Garden
25 papers
Beth Beadle
24 papers
Clifton Fuller
23 papers · 6 as a fellow
Wayne Hofstetter
23 papers
Brandon Gunn
21 papers
Brian Weston
21 papers
Manoop Bhutani
21 papers
Steven Frank
21 papers
David Rosenthal
20 papers

Grants

Analysis of High Dimensional Genomic Dataset to Reveal Mechanistic Insights on Divergent Outcomes of Head and Neck Cancer Using System Biology Modeling Coupled with Experimental Validation
National Institute of Dental and Craniofacial Research · R01
PI · $1.9M · University of Pittsburgh at Pittsburgh
2025–2028
Targeting Non-Canonical p16 Signaling to Improve Radiation Response and Outcome in Head and Neck Cancer
National Institute of Dental and Craniofacial Research · R01
Contact PI · $2.3M · University of Pittsburgh at Pittsburgh
2023–2028
Head and Neck Cancer SPORE
National Cancer Institute · P50
Contact PI · $10.5M · University of Pittsburgh at Pittsburgh
2004–2027
Synthetic Lethal Targeting of CREBBP/EP300 in Head and Neck Squamous Cell Carcinoma
National Institute of Dental and Craniofacial Research · R01
PI · $2.8M · Yale University
2019–2026

Clinical trials

Transoral Surgical Resection Followed by De-escalated Adjuvant IMRT in Resectable p16+ Locally Advanced Oropharynx Cancer
Principal investigator · Recruiting · Phase 2
Heath Skinner
2022–2030
Low Level Laser Therapy for Radiation Induced Dermatitis in H & N Squamous Cell Carcinoma
Principal investigator · Completed
Heath Skinner
2015–2020
4-Dimensional CT Derived Ventilation Versus SPECT Aerosol Ventilation in Patients With Thoracic Malignancies
Principal investigator · Completed · Phase 2
M.D. Anderson Cancer Center
2007–2018
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
Site PI · Recruiting · Phase 2
ECOG-ACRIN Cancer Research Group
2016–2027