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Igor Astsaturov

Professor, Department of Hematology/Oncology · Temple University Hospital

Credentials: · · · ·

History

Temple University Hospital
Present
Temple University Hospital
Present

Hematology and Medical Oncology
Temple University Hospital
1988–1991
Internal Medicine
1985–1988
Doctor of Medicine
1981–1985

Research

A framework for advancing our understanding of cancer-associated fibroblasts
Review · Nature reviews. Cancer · 2020 · 3,123 citations
Aurora A kinase (AURKA) in normal and pathological cell division
Review · Cellular and Molecular Life Sciences · 2013 · 383 citations
Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast-Driven Nutritional Support and Immunosuppression
Cancer Discovery · 2021 · 184 citations

Barbara Burtness
9 papers
SC
Steven Cohen
9 papers
Louis Weiner
7 papers
Crystal Denlinger
6 papers
YZ
Yan Zhou
6 papers · 2 as a resident
ED
Efrat Dotan
5 papers
Joshua Meyer
5 papers · 1 as a fellow
Michael Hall
5 papers
HC
Harry Cooper
4 papers
Namrata Vijayvergia
4 papers
NM
Neal Meropol
4 papers
Paul Engstrom
4 papers

Grants

Targeting Anoctamin 6 to Disrupt Trogocytosis of Cancer-Associated Fibroblasts
National Cancer Institute · R01
Contact PI · $1.3M · Research Inst of Fox Chase Can Ctr
2025–2030
A Phase I Proof-of-Concept Study of CBL0137 Combined with Ipilimumab and Nivolumab Therapy in Locally Advanced or Metastatic Melanoma
National Cancer Institute · R21
Contact PI · $472.4K · Research Inst of Fox Chase Can Ctr
2023–2026
Divergent Functions of ERK2 Substrate Binding Domains in Pathogenesis of KRAS-Driven Pancreatic Cancer
National Cancer Institute · R03
Contact PI · $188K · Research Inst of Fox Chase Can Ctr
2023–2025
Neoadjuvant Stroma Modification in Pancreatic Cancer
National Cancer Institute · R21
Contact PI · $459.6K · Research Inst of Fox Chase Can Ctr
2021–2024

Clinical trials

A Trial of ZD6474, Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiation Therapy Followed by Surgery
Principal investigator · Completed · Phase 1
Fox Chase Cancer Center
2008–2011
A Study to Evaluate Safety, Efficacy, and Pharmacokinetics in Participants With Advanced Solid Tumors
Sub-investigator · Unknown · Phase 1, Phase 2
Eutilex
2021–2025