
Irene Ghobrial
Lavine Family Chair for Preventative Cancer Therapies · Mass General Brigham
Credentials: · · · ·
History
- Present
- Present
Center for Early Detection and Interception of Blood Cancers · Mass General Brigham



- 1995–1998
Cairo University School of Medicine
Research
Biological properties of extracellular vesicles and their physiological functions
Journal of Extracellular Vesicles · 2015 · 4,771 citations
BET bromodomain inhibition as a therapeutic strategy to target c-Myc
Cell · 2011 · 2,410 citations
Blood · 2022 · 1,363 citations

96 papers

71 papers

55 papers

53 papers

45 papers
- RS
36 papers

24 papers

22 papers
Grants
- 2026–2031
Precision Interception for MGUS/SMM
National Cancer Institute · P01
Contact PI · $2.5M · Dana-Farber Cancer Inst
- 2024–2029
Myeloma Multidimensional Precancer Atlas
National Cancer Institute · U01
Contact PI · $5.6M · Dana-Farber Cancer Inst
- 2022–2029
Molecular Prediction of Myeloma Initiation Molecular Prediction of Myeloma Initiation
National Cancer Institute · R35
Contact PI · $5.1M · Dana-Farber Cancer Inst
- 2022–2027
Molecular Prediction of Myeloma in African Americans
National Cancer Institute · U01
Contact PI · $2.6M · Dana-Farber Cancer Inst
Clinical trials
- 2023–2040
CAR- PRISM (PRecision Intervention Smoldering Myeloma)
Principal investigator · Active not recruiting · Phase 2
Dana-Farber Cancer Institute
- 2022–2030
Immuno-PRISM (PRecision Intervention Smoldering Myeloma)
Principal investigator · Recruiting · Phase 2
Irene Ghobrial, MD
- 2018–2033
Predicting Progression of Developing Myeloma in a High-Risk Screened Population (PROMISE)
Principal investigator · Enrolling by invitation
Dana-Farber Cancer Institute
- 2017–2026
Principal investigator · Active not recruiting · Phase 2
Dana-Farber Cancer Institute


