James Abbruzzese
D.C.I. Distinguished Professor Emeritus of Medical Oncology · Duke Department of Medicine
Credentials: · ·
History
- Present
Duke Department of Medicine
- Present
Duke Department of Medicine
Research
The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
New England Journal of Medicine · 2000 · 2,013 citations
Review · The Lancet · 2004 · Last of 4 authors · 1,673 citations
Phase II trial of curcumin in patients with advanced pancreatic cancer
Clinical Cancer Research · 2008 · 987 citations
99 papers
88 papers
51 papers
46 papers
- GV
42 papers
- HX
41 papers · 13 as a fellow
40 papers
39 papers
Grants
- 2022–2025
Adapting K-MDS to Detect KRAS-Mutant ctDNA
National Cancer Institute · R21
PI · $188.2K · Duke University
- 1997–2025
Cancer Center Support Grant (CCSG)
National Cancer Institute · P30
Project lead · $1.3M · Duke University
- 2014–2023
National Cancer Institute · UM1
Contact PI · $6.1M · Duke University
- 2003–2011
National Cancer Institute · P20
Contact PI · $5.4M · University of Tx Md Anderson Can Ctr
Clinical trials
- 2000
SU5416 and Irinotecan in Treating Patients With Advanced Colorectal Cancer
Principal investigator · Completed · Phase 1, Phase 2
National Cancer Institute (NCI)
- 2005–2012
S0414 Cetuximab, Combo Chemo, and RT in Locally Advanced Esophageal Cancer
Study chair · Terminated · Phase 2
SWOG Cancer Research Network
- 2004
S0304 Induct Chemo Then Chemo-RT in Pts w/Locally Advanced Adenocarcinoma of the Rectum
Study chair · Withdrawn · Phase 2
SWOG Cancer Research Network