James Kirkland
Director, Center for Advanced Gerotherapeutics Medicine · Cedars-Sinai Medical Center
Credentials: · · · · ·
History
- Present
Center for Advanced Gerotherapeutics Medicine · Cedars-Sinai Medical Center
- 1980–1982
Endocrinology, Diabetes, and Metabolism
- 1977–1980
Internal Medicine
- 1973–1977
Research
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
Nature · 2011 · 2,951 citations
The Achilles' heel of senescent cells: from transcriptome to senolytic drugs
Aging Cell · 2015 · 1,984 citations
Senolytics improve physical function and increase lifespan in old age
Nature Medicine · 2018 · 1,827 citations
- NL
44 papers
33 papers
26 papers
22 papers
19 papers
18 papers
16 papers · 4 as a fellow
16 papers
Grants
- 2025–2030
Los Angeles Claude D. Pepper Older Americans Independence Center
National Institute on Aging · P30
Project lead · $678.1K · Cedars-Sinai Medical Center
- 2019–2029
Translational Geroscience Network
National Institute on Aging · R33
Contact PI · $5.5M · Cedars-Sinai Medical Center
- 1997–2027
Effect of Aging on Preadipocyte Differentiation
National Institute on Aging · R37
Contact PI · $6.6M · Cedars-Sinai Medical Center
- 2020–2025
National Institute on Aging · R01
Contact PI · $1.9M · Mayo Clinic Rochester
Clinical trials
- 2021–2022
COVFIS-HOME: COVID-19 Pilot Study of Fisetin to Alleviate Dysfunction and Decrease Complications
Principal investigator · Completed · Phase 2
James L. Kirkland, MD, PhD
- 2004–2009
Use of MCT Oil for Enhancement of Weight Loss and Glycemic Control in Obese Diabetic Patients
Study chair · Completed · Phase 1, Phase 2
Boston Medical Center
- 2003–2008
Use of MCT Oil for Enhancement of Weight Loss in Obese Patients
Study chair · Completed
Boston Medical Center