Sign inJoin waitlistJoin the waitlist

Jana Portnow

Medical Oncologist · City of Hope National Medical Center

Credentials: · · ·

History

City of Hope National Medical Center
Present

Medical Oncology
1997–1999
Internal Medicine
1994–1997
University of Rochester School of Medicine and Dentistry
1990–1994

Research

Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy
Case report · New England Journal of Medicine · 2016 · 1,520 citations
Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma
Clinical Cancer Research · 2015 · 643 citations
First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma
Journal of Translational Medicine · 2018 · 425 citations

Behnam Badie
19 papers
Louis Nabors
12 papers
LJ
Larry Junck
9 papers
Massimo D'Apuzzo
9 papers
DS
Dennis Shrieve
8 papers
Henry Brem
8 papers
Maciej Mrugala
8 papers
PW
Patrick Wen
8 papers
Allen Sills
7 papers
Herbert Newton
7 papers
Jona Hattangadi-Gluth
7 papers
Nicholas Butowski
7 papers

Grants

Development of Small Molecule Inhibitors and Biologic Agents for Treatment of Glioblastoma Using Intracerebral Microdialysis and Signatures of Vulnerability
National Cancer Institute · U19
Contact PI · $5.3M · Beckman Research Institute/City of Hope
2021–2027
A Phase I Study of Intracranially Administered Carboxylesterase-Expressing Neural Stem Cells in Combination with Intravenous Irinotecan in Patients with Recurrent High Grade Gliomas
National Cancer Institute · R01
Contact PI · $2.3M · Beckman Research Institute/City of Hope
2015–2021
Phase 1 Study of Neural Stem Cells & 5-FC/Leucovorin for the Treatment of Recurrent High Grade Gliomas
Food and Drug Administration · R01
Contact PI · $595.3K · Beckman Research Institute/City of Hope
2014–2017
A Pilot Study of 5-FC and Genetically-Modified Neural Stem Cells to Treat Gliomas
National Cancer Institute · R21
Contact PI · $730.4K · Beckman Research Institute/City of Hope
2009–2012

Clinical trials

FPS-ZM1 With or Without Dexamethasone for Controlling Post Operative Cerebral Edema in Patients With Glioblastoma
Principal investigator · Not yet recruiting · Phase 1
City of Hope Medical Center
2027–2028
Dexamethasone and Azeliragon for Management of Post-Resection Cerebral Edema in Patients with Glioblastoma
Principal investigator · Withdrawn · Phase 1
City of Hope Medical Center
2024
Multiple Intracerebral Doses of Neural Stem Cell-Based Virotherapy (NSC-CRAd-S-pk7) for the Treatment of Recurrent High-Grade Gliomas
Principal investigator · Recruiting · Phase 1
City of Hope Medical Center
2023–2027
Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment
Principal investigator · Recruiting · Phase 1, Phase 2
National Cancer Institute (NCI)
2023–2027