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JC

Jean Chan

Endocrinology, Diabetes & Metabolism

Credentials: · ·

History

Internal Medicine

Research

Recombinant human leptin in women with hypothalamic amenorrhea
New England Journal of Medicine · 2004 · 621 citations
The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men
Journal of Clinical Investigation · 2003 · First of 5 authors · 473 citations
Circulating resistin levels are not associated with obesity or insulin resistance in humans and are not regulated by fasting or leptin administration: cross-sectional and…
The Journal of Clinical Endocrinology & Metabolism · 2003 · 435 citations

Christos Mantzoros
30 papers
PR
Patricia Raciti
5 papers
AD
Alex Depaoli
4 papers
Alina Gavrila-Filip
4 papers
EO
Elif Oral
4 papers
Kyriakie Sarafoglou
4 papers
Mitchell Shiffman
4 papers
RA
Richard Auchus
4 papers · 2 as a fellow
Arun Sanyal
3 papers
CF
Catherine Frenette
3 papers
GG
Guadalupe Garcia-Tsao
3 papers
Katie Suddarth
3 papers

Grants

Leptin in Neuroendocrine Function
National Center for Research Resources · K23
Contact PI · $651.1K · Beth Israel Deaconess Medical Center
2004–2009

Clinical trials

Emricasan, a Caspase Inhibitor, for Evaluation in Subjects With Non-Alcoholic Steatohepatitis (NASH) Fibrosis
Study chair · Completed · Phase 2
Conatus Pharmaceuticals Inc.
2016–2019
Emricasan, a Caspase Inhibitor, for Treatment of Subjects With Decompensated NASH Cirrhosis
Study director · Unknown · Phase 2
Conatus Pharmaceuticals Inc.
2017–2019
Extension Study of Protocol DFA102 to Examine the Long-Term Safety, Tolerability, and Effect on Body Weight of Pramlintide Administered in Combination With Metreleptin
Study director · Completed · Phase 2
AstraZeneca
2008–2009