
John Bissler
Director, Tuberous Sclerosis Center of Excellence, Peds Nephrology. · University of Tennessee College of Medicine
Credentials: · · · · ·
History
- Present
Tuberous Sclerosis Center of Excellence · University of Tennessee College of Medicine
- Present
Colllege of Medicine Division · University of Tennessee College of Medicine
- Present
Professor Division · University of Tennessee College of Medicine

- 1985–1988
1981–1985
Research
Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis
New England Journal of Medicine · 2008 · First of 12 authors · Corresponding · 968 citations
The Lancet · 2013 · First of 17 authors · Corresponding · 682 citations
Pediatric Neurology · 2021 · 553 citations

14 papers

8 papers · 1 as a fellow
- MF
8 papers

7 papers
- JH
7 papers

6 papers

6 papers

6 papers
Grants
- 2016–2017
Pediatric Nephrology Tribute to Russell Chesney, M.D.
National Institute of Diabetes and Digestive and Kidney Diseases · R13
Contact PI · $10K · University of Tennessee Health Sci Ctr
- 2003–2009
DNA Replication Fork: Pausing, Recombination and Disease
National Institute of Diabetes and Digestive and Kidney Diseases · R01
Contact PI · $1.2M · Cincinnati Childrens Hosp Med Ctr
- 2003–2008
General Clinical Research Center
National Center for Research Resources · M01
Project lead · $139.9K · Cincinnati Childrens Hosp Med Ctr
- 2003–2006
Utility of Rapamycin for the Treatment of Renal Angiomy*
National Cancer Institute · R21
Contact PI · $548.5K · Cincinnati Childrens Hosp Med Ctr
Clinical trials
- 2008–2013
Principal investigator · Completed · Phase 1, Phase 2
Children's Hospital Medical Center, Cincinnati
- 2008–2013
Tuberous Sclerosis Complex Natural History Study: Renal Manifestations
Principal investigator · Completed
Children's Hospital Medical Center, Cincinnati
- 2005–2013
RAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAM
Principal investigator · Completed · Phase 1, Phase 2
Children's Hospital Medical Center, Cincinnati
- 2002–2006
Rapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAM
Principal investigator · Completed · Phase 2
Children's Hospital Medical Center, Cincinnati
