John Ligon

Clinical trials

• IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent Pediatric High-grade Glioma (pHGG) and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (ndDIPG)

  Principal investigator · Not yet recruiting · Phase 1

  University of Florida

  2026–2045
• Peds CHAMP1ON - Hematopoietic Stem Cell And Monoclonal Antibody PD-1 Blockade for RecurreNt Pediatric High-Grade Glioma

  Principal investigator · Active not recruiting · Phase 1

  University of Florida

  2025–2032
• Adoptive T Cell Therapy, DC Vaccines, and Hematopoietic Stem Cells Combined With Immune checkPOINT Blockade in Patients With Medulloblastoma

  Principal investigator · Recruiting · Phase 1

  University of Florida

  2025–2028
• RNA Lipid Particles Targeting Pediatric Recurrent Intracranial Malignancies and Other systEmic Solid Tumors

  Study chair · Active not recruiting · Phase 1, Phase 2

  University of Florida

  2025–2035