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John Metcalfe

Professor · University of California (San Francisco) School of Medicine

Credentials: · · · · ·

History

University of California (San Francisco) School of Medicine
Present

Pulmonary Disease and Critical Care Medicine
University of California-San Francisco
2006–2009
Internal Medicine
University of California-San Francisco
2003–2006
California State Polytechnic University-Humboldt
1995–1999
California State Polytechnic University-Humboldt
1994–1998

Research

Gamma interferon release assays for detection of Mycobacterium tuberculosis infection
Review · Clinical Microbiology Reviews · 2014 · 661 citations
Interferon-gamma release assays for the diagnosis of latent tuberculosis infection in HIV-infected individuals: a systematic review and meta-analysis
Systematic review or meta-analysis · Journal of acquired immune deficiency syndromes · 2011 · 236 citations
Interferon-γ release assays for active pulmonary tuberculosis diagnosis in adults in low- and middle-income countries: systematic review and meta-analysis
Systematic review or meta-analysis · The Journal of Infectious Diseases · 2011 · First of 7 authors · 209 citations

Adithya Cattamanchi
16 papers · 1 as a fellow
Monica Gandhi
14 papers
Philip Hopewell
14 papers
David Dowdy
5 papers · 3 as a resident
Max O'Donnell
5 papers
DK
David Katzenstein
4 papers
Laurence Huang
4 papers
Payam Nahid
4 papers
AC
Aaron Chin
3 papers · 2 as a resident
CD
Claudia Denkinger
3 papers
DB
David Bangsberg
3 papers
JF
Jennifer Flood
3 papers

Grants

A Novel Cartridge-Based Sequencing Solution for Decentralized M. tuberculosis Resistance Detection
National Institute of Allergy and Infectious Diseases · R01
Contact PI · $2.8M · University of California, San Francisco
2023–2028
Handheld and Population-Based Sequencing for Rapid Detection of New and Repurposed Drug Resistance in M. tuberculosis
National Institute of Allergy and Infectious Diseases · R01
Contact PI · $3.7M · University of California, San Francisco
2021–2027
Comprehensive Characterization of Rv0678 Bedaquiline Resistance-Conferring Polymorphisms
National Institute of Allergy and Infectious Diseases · R21
Contact PI · $450.5K · University of California, San Francisco
2024–2026
Training for Research Excellence and MeNtorship in Tuberculosis (TRENT)
Fogarty International Center · D43
Contact PI · $2.6M · University of California, San Francisco
2013–2024

Clinical trials

Pragmatic Use of Next-generation Sequencing for Management of Drug-resistant Tuberculosis
Principal investigator · Recruiting
University of California, San Francisco
2024–2027
Clofazimine- and Rifapentine-Containing Treatment Shortening Regimens in Drug-Susceptible Tuberculosis: The CLO-FAST Study
Study chair · Terminated · Phase 2
National Institute of Allergy and Infectious Diseases (NIAID)
2021–2025