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John Sheppard

Physician · Sentara Norfolk General Hospital

Credentials: · · ·

History

Sentara Norfolk General Hospital
Present

Ophthalmology
UPMC Medical Education
1983–1986
Pediatrics
University of Virginia Medical Center
1978–1979
Warren Alpert Medical School of Brown University
1974–1978

Research

Adalimumab for prevention of uveitic flare in patients with inactive non-infectious uveitis controlled by corticosteroids (VISUAL II): a multicentre, double-masked, randomised,…
The Lancet · 2016 · 422 citations
Ocular TRUST: nationwide antimicrobial susceptibility patterns in ocular isolates
American Journal of Ophthalmology · 2008 · 189 citations
Lifitegrast ophthalmic solution 5.0% for treatment of dry eye disease: results of the OPUS-1 phase 3 study
Ophthalmology · 2014 · First of 9 authors · 185 citations

PK
Paul Karpecki
6 papers
CF
Charles Foster
5 papers
EH
Edward Holland
5 papers
MT
Melissa Toyos
5 papers
AC
Albert Cheung
4 papers
Esen Akpek
4 papers
JT
Joseph Tauber
4 papers
BS
Barry Schechter
3 papers
DG
Damien Goldberg
3 papers
GT
Gail Torkildsen
3 papers
GO
George Ousler
3 papers
JH
John Hovanesian
3 papers

Grants

Proof of Concept for Antimicrobial Properties of Lacritin in vivo
National Eye Institute · R41
Contact PI · $128.8K · Eyerx Research, Inc.
2010–2011
Stimulation of Tear Secretion by a Novel Glycoprotein
National Eye Institute · R42
Contact PI · $682K · Eyerx Research, Inc.
2004–2010
Stimulation of Tear Secretion by a Novel Glycoprotein
National Eye Institute · R41
Contact PI · $104.9K · Eyerx Research, Inc.
2004–2006
Idiotype Immune Modulation of Murine Chlamydia Infection
National Eye Institute · F32
Contact PI · $33K · University of California, San Francisco
1988

Clinical trials

Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Ophthalmic Solution in Non-Infectious Anterior Uveitis
Principal investigator · Completed · Phase 3
Eyegate Pharmaceuticals, Inc.
2016–2018
Safety and Efficacy of KPI-121 in Subjects With Inflammatory Meibomian Gland Disease
Principal investigator · Completed · Phase 2
Kala Pharmaceuticals, Inc.
2014–2016
A Phase 1/2, RU-101 Ophthalmic Solution in Patients With Severe Dry Eye
Principal investigator · Completed · Phase 1, Phase 2
R-Tech Ueno, Ltd.
2013–2014
A Placebo Controlled Comparison of Topical Zirgan Versus Genteal Gel for the Treatment of Adenovirus Conjunctivitis
Principal investigator · Completed · Phase 4
Lifelong Vision Foundation
2012–2016