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Jose Leone

, Director, Program for Breast Cancer in Men · Mass General Brigham

Credentials: · · · · · ·

History

Boston Medical Center-Brighton
Present
Mass General Brigham
Present

UPMC
2008–2010
Internal Medicine
University of Miami/Jackson Health System
2005–2008
Doctor of Medicine
2001–2005

Research

Sensitive Detection of Mono- and Polyclonal ESR1 Mutations in Primary Tumors, Metastatic Lesions, and Cell-Free DNA of Breast Cancer Patients
Clinical Cancer Research · 2016 · 160 citations
Intrinsic Subtype Switching and Acquired ERBB2/HER2 Amplifications and Mutations in Breast Cancer Brain Metastases
JAMA Oncology · 2017 · 147 citations
Immunotherapy in Breast Cancer
Review · International Journal of Molecular Sciences · 2024 · Last of 3 authors · Corresponding · 134 citations

Nancy Lin
36 papers
Sara Tolaney
29 papers
Eric Winer
19 papers
Rachel Freedman
13 papers
Michael Hassett
12 papers
AB
Adam Brufsky
8 papers
Rohit Bhargava
6 papers
RH
Ronald Hamilton
6 papers
Adrienne Waks
5 papers
IK
Ian Krop
5 papers
JB
Jennifer Bellon
4 papers
Peter Lucas
4 papers

Grants

Predicting Endocrine Therapy Response In Male Breast Tumors
National Cancer Institute · R37
PI · $1.8M · Univ of North Carolina Chapel Hill
2024–2029

Clinical trials

ETHAN - ET for Male BC
Principal investigator · Recruiting · Phase 2
Jose Pablo Leone
2023–2036
Tucatinib + Abemaciclib + Herceptin for HER2+ MBC
Principal investigator · Withdrawn · Phase 1
Dana-Farber Cancer Institute
2020
GDC-0084 in Combination With Trastuzumab for Patients With HER2-Positive Breast Cancer Brain Metastases
Principal investigator · Terminated · Phase 2
Dana-Farber Cancer Institute
2019–2024
Neratinib +/- Fulvestrant in HER2+, ER+ Metastatic Breast Cancer
Principal investigator · Terminated · Phase 2
Dana-Farber Cancer Institute
2017–2021