Joseph Zabner
Professor of Internal Medicine-Pulmonary, Critical Care and Occupational Medicine · University of Iowa
Credentials: · ·
History
Present
University of Iowa Hospitals & Clinics
Parkland Hospital
Research
TLR4 mutations are associated with endotoxin hyporesponsiveness in humans
Nature Genetics · 2000 · 1,587 citations
Cellular and molecular barriers to gene transfer by a cationic lipid
Journal of Biological Chemistry · 1995 · First of 5 authors · 1,136 citations
Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung
Nature · 2012 · Last of 16 authors · 646 citations
76 papers
48 papers
33 papers
21 papers
18 papers
11 papers · 5 as a resident
10 papers · 2 as a resident
8 papers
Grants
- 2025–2030
Pathogenesis and Therapeutic Approaches in Primary Ciliary Dyskinesia
National Heart, Lung, and Blood Institute · P01
Project lead · $777.6K · University of Iowa
- 2020–2027
Molecular Therapies for Cystic Fibrosis Lung Disease
National Heart, Lung, and Blood Institute · P01
Project lead · $920.4K · University of Iowa
- 1998–2025
Precision Medicine Center for Cystic Fibrosis
National Institute of Diabetes and Digestive and Kidney Diseases · P30
Project lead · $3.3M · University of Iowa
- 2008–2024
Origins of Cystic Fibrosis Airway Disease
National Heart, Lung, and Blood Institute · P01
Project lead · $5.7M · University of Iowa
Clinical trials
- 2013–2018
Aerosolized Hypertonic Xylitol Versus Hypertonic Saline in Cystic Fibrosis (CF) Subjects
Principal investigator · Completed · Phase 1, Phase 2
Joseph Zabner
- 2011–2015
Inhaled Xylitol Versus Saline in Stable Subjects With Cystic Fibrosis
Principal investigator · Completed · Phase 1, Phase 2
Joseph Zabner