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Laura Klesse

Professor · University of Texas Southwestern Medical Center

Credentials: · · ·

History

University of Texas Southwestern Medical Center
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University of Texas Southwestern Medical Center
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Children's Health Andrews Institute
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Children's Health - Children's Medical Center of Dallas
2002–2005
Pediatric Hematology Oncology
University of Texas Southwestern Medical Center
2001–2002
Univ of Texas Southwestern Med Sch at Dallas
1997–2001
University of Notre Dame
1988–1992

Research

Neurotrophins use the Erk5 pathway to mediate a retrograde survival response
Nature Neuroscience · 2001 · 360 citations
Mouse tumor model for neurofibromatosis type 1
Science · 1999 · 293 citations
Requirement for nitric oxide activation of p21(ras)/extracellular regulated kinase in neuronal ischemic preconditioning
Proceedings of the National Academy of Sciences of the United States of America · 2000 · 261 citations

Daniel Bowers
8 papers
Kathleen Ludwig
8 papers
Michael Fisher
8 papers
Karen Rabin
7 papers
KH
Kenneth Heym
7 papers
Monica Gramatges
7 papers
Nicole Ullrich
7 papers
Rodrigo Erana
7 papers
VH
Van Huynh
7 papers
David Viskochil
6 papers
Elizabeth Schorry
6 papers
Juan Bernini
6 papers

Clinical trials

Evaluation of [18F]FLT PET/CT as an Early Predictor of Outcome in Pediatric Solid Tumors
Principal investigator · Withdrawn · Early phase 1
University of Texas Southwestern Medical Center
2019–2024
Study of Cabozantinib With Selumetinib for Plexiform Neurofibromas
Site PI · Recruiting · Phase 1
Girish Dhall, MD
2026–2034
Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1
Site PI · Recruiting · Phase 2
University of Alabama at Birmingham
2025–2032
A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1
Site PI · Recruiting · Phase 2
Healx Limited
2025–2028