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LP

Leon Pappas

Physician · Brigham and Women's Hospital

Credentials: · · · · · ·

History

Brigham and Women's Hospital
2026–Present

Brigham and Women's Hospital
2022–2024
Internal Medicine
Massachusetts General Hospital
2018–2021
Boston University School of Medicine
2014–2018

Research

Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker
Cancer Discovery · 2023 · 82 citations
Genomic landscape of clinically acquired resistance alterations in patients treated with KRASG12C inhibitors
Annals of Oncology · 2025 · 49 citations
Rational development of a protective P. vivax vaccine evaluated with transgenic rodent parasite challenge models
Scientific Reports · 2017 · 45 citations

AP
Aparna Parikh
9 papers
RC
Ryan Corcoran
6 papers
BC
Bennett Caughey
5 papers · 1 as a fellow
David Ting
4 papers
SK
Samuel Klempner
4 papers
AZ
Andrew Zhu
3 papers
Anthony Iafrate
3 papers
JA
Jill Allen
3 papers
Lipika Goyal
3 papers
AB
Andrea Bocobo
2 papers · 2 as a resident
Andrew Creadore
2 papers
Apurva Jain
2 papers

Clinical trials

IKS04 Regimen in Advanced Solid Tumors That Express CA242
Site PI · Not yet recruiting · Phase 1
Iksuda Therapeutics Ltd.
2026–2029
A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer
Site PI · Recruiting · Phase 1
Sutro Biopharma, Inc.
2025–2028
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
Site PI · Recruiting · Phase 1, Phase 2
Verastem, Inc.
2025–2028
A Study of PT0253 in Participants With KRAS G12D Mutated Advanced Solid Tumors
Site PI · Recruiting · Phase 1
PAQ Therapeutics, Inc.
2024–2027