Leslie Kean

Director, Stem Cell Transplant Center · Mass General Brigham

Credentials: · · · · ·

History

BMT Core - Pediatric Transplantation and Cellular Therapy Consortium (PTCTC): Providing Clinical Trial Access For Children With Life Threatening Diseases
National Heart, Lung, and Blood Institute · UG1
PI · $513.4K · National Marrow Donor Program
2024–2031
Optimizing HCT Outcomes: A Multi-Omic Investigation
National Heart, Lung, and Blood Institute · R01
Contact PI · $3.9M · Boston Children's Hospital
2025–2030
Novel Approaches to Inducing Lung Allograft Tolerance in NHPs
National Institute of Allergy and Infectious Diseases · U19
Project lead · $5.9M · Massachusetts General Hospital
2023–2028
Mechanisms and Therapy of Chronic Graft-vs.-Host Disease
National Heart, Lung, and Blood Institute · P01
Project lead · $2.3M · Dana-Farber Cancer Inst
2022–2027

Precision Diagnostics in Inflammatory Bowel Disease, Cellular Therapy and Transplantation (The PREDICT Trial)
Principal investigator · Enrolling by invitation
Boston Children's Hospital
2017–2032
Abatacept as GVHD Prophylaxis Phase 2
Principal investigator · Completed · Phase 2
Boston Children's Hospital
2013–2024
Pilot of Abatacept-based Immunosuppression for Prevention of Acute GvHD During Unrelated Donor HCT
Principal investigator · Completed · Phase 2
Boston Children's Hospital
2009–2013
Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis
Site PI · Recruiting · Phase 2
Boston Children's Hospital
2022–2028