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LL

Lionel Lewis

(Section Chief, Clinical Pharmacology) · Dartmouth-Hitchcock/Mary Hitchcock Memorial Hospital

Credentials: · · ·

History

Clinical Pharmacology) Section · Dartmouth-Hitchcock/Mary Hitchcock Memorial Hospital
Present
NCCC Early Phase Clinical Trials Oncology Group · Geisel School of Medicine
Present
Geisel School of Medicine
Present

University Hospital of Wales
1980–1983
Dartmouth Cancer Center
1977–1980
UNIV OF WALES COLL OF MED, CARDIFF, WALES
1973–1977
Trinity College, Univ of Cambridge, BA 1974
1970–1974

Research

Safety and Efficacy of Nivolumab in Combination With Ipilimumab in Metastatic Renal Cell Carcinoma: The CheckMate 016 Study
Journal of Clinical Oncology · 2017 · 415 citations
Phase I and pharmacokinetic study of YM155, a small-molecule inhibitor of survivin
Journal of Clinical Oncology · 2008 · 212 citations
Phase I and pharmacokinetic study of sorafenib in patients with hepatic or renal dysfunction: CALGB 60301
Journal of Clinical Oncology · 2009 · 171 citations

Marc Ernstoff
16 papers
GT
Gregory Tsongalis
9 papers
Mark Ratain
7 papers
AD
Alexey Danilov
6 papers
Camilo Fadul
6 papers
DN
David Nierenberg
6 papers
NR
Nandi Reddy
6 papers
Peter Kaufman
6 papers
RP
Raymond Perez
6 papers
AM
Antonius Miller
5 papers
SC
Shodeinde Coker
5 papers · 3 as a fellow
Uday Dandamudi
5 papers

Grants

Cancer Center Support Grant
National Cancer Institute · P30
Project lead · $4M · Dartmouth College
1997–2029
7HP349, an Integrin Activator to Treat Patients With Anti-PD-1 Resistant Solid Tumors
National Cancer Institute · R44
PI · $2M · 7 Hills Pharma, Llc
2023–2025
Development of 7HP349, an Oral Integrin Activator to Enhance Therapeutic Responses to Immune Checkpoint Inhibitors
National Cancer Institute · R44
PI · $2M · 7 Hills Pharma, Llc
2020–2022
Dartmouth Center for Cancer Nanotechnology Excellence
National Cancer Institute · U54
Project lead · $681.1K · Dartmouth College
2010–2016

Clinical trials

HCQ in Resectable Localized Prostate Cancer
Principal investigator · Recruiting · Early phase 1
Lionel.D.Lewis, MD
2026–2029
A Study of BNC105P Combined With Ibrutinib
Principal investigator · Completed · Phase 1
Dartmouth-Hitchcock Medical Center
2018–2021
Dose Escalation Study of Nelfinavir Plus MLN9708 in Patients With Advanced Solid Tumors or Lymphoma
Principal investigator · Withdrawn · Phase 1
Dartmouth-Hitchcock Medical Center
2016–2017
A Phase 1/2, Open-label Study to Evaluate the Safety and Antitumor Activity of MEDI0680 (AMP-514) in Combination With Durvalumab Versus Nivolumab Monotherapy in Participants With Select Advanced Malignancies
Principal investigator · Completed · Phase 1, Phase 2
MedImmune LLC
2014–2020