Marc Simon
Director of Pulmonary Vascular Disease and the Pulmonary Hypertension Comprehensive Care Center · University of California (San Francisco) School of Medicine
Credentials: · · · · · ·
History
- Present
Pulmonary Vascular Disease and the Pulmonary Hypertension Comprehensive Care Center · University of California (San Francisco) School of Medicine
- 2005–2007
- 2001–2004
- 1990–1994
Research
Circulation · 2012 · 416 citations
Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension
Journal of Clinical Investigation · 2016 · 389 citations
European Heart Journal · 2014 · 306 citations
16 papers
- RK
15 papers
14 papers
- JG
11 papers
10 papers
9 papers
- HC
9 papers
8 papers
Grants
- 2018–2026
National Institute on Aging · R01
Contact PI · $3.2M · University of California, San Francisco
- 2011–2023
Therapeutic Targeting of Vascular Subphenotypes of Lung Disease
National Heart, Lung, and Blood Institute · P01
Project lead · $2M · University of Pittsburgh at Pittsburgh
Clinical trials
- 2019–2020
Oral CXA-10 in Pulmonary Arterial Hypertension
Principal investigator · Terminated · Phase 2
Gladwin, Mark, MD
- 2017–2022
Phase 1/1b Study With Nab-sirolimus for Patients With Severe Pulmonary Arterial Hypertension
Principal investigator · Completed · Phase 1
Aadi Bioscience, Inc.
- 2012–2017
Inhaled Nitrite in Subjects With Pulmonary Hypertension
Principal investigator · Completed · Phase 2
Schmidhofer, Mark, MD
- 2019–2026
Metformin for Pulmonary Hypertension HFpEF
Study director · Completed · Phase 2
University of California, San Francisco