Margaret Sedensky
Professor, Department of Anesthesiology and Pain Medicine · University of Washington
Credentials: · · ·
History
- Present
- 1980–1984
Anesthesiology
Research
mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome
Science · 2013 · 447 citations
Mitochondrial complex I deficiency increases protein acetylation and accelerates heart failure
Cell Metabolism · 2013 · 392 citations
Cell Biology of the Mitochondrion
Review · Genetics · 2017 · 305 citations
92 papers
- MF
5 papers · 2 as a resident
4 papers
4 papers
- CC
3 papers
- EO
3 papers · 1 as a resident
3 papers
- HC
2 papers
Grants
- 2019–2023
The Role of Ketone Metabolism in Sequelae Resulting from Volatile Anesthetic Exposure.
National Institute of General Medical Sciences · R01
Contact PI · $744K · Seattle Children's Hospital
- 2014–2023
A Mouse Model Linking Anesthetic Sensitivity to Mitochondrial Function
National Institute of General Medical Sciences · R01
Contact PI · $4.4M · Seattle Children's Hospital
- 1999–2011
Mitochondrial Effects on Sensitivity to Anesthetics
National Institute of General Medical Sciences · R01
Contact PI · $4.2M · Seattle Children's Hospital
- 1989–1994
Molecular Pharmacology of Anesthetics in c Elegans
National Institute of General Medical Sciences · R29
Contact PI · $492.2K · Case Western Reserve University