
Mark Sellmyer
Director of the PET Center · University of Pennsylvania Health System
Credentials: · · · · · ·
History
- Present
PET Center · University of Pennsylvania Health System
- Present
Center for Translational Chemical Biology · University of Pennsylvania Health System
Sloan-Kettering Cancer Center
- 2012–2015
Kaiser Permanente Medical Center

Research
A microbiome-dependent gut-brain pathway regulates motivation for exercise
Nature · 2022 · 229 citations
Physiologic, histologic, and imaging features of retained products of conception
Radiographics · 2013 · First of 5 authors · 125 citations
Bacterial infection imaging with [18F]fluoropropyl-trimethoprim
Proceedings of the National Academy of Sciences of the United States of America · 2017 · First of 9 authors · Corresponding · 116 citations

9 papers

6 papers

5 papers · 4 as a resident

3 papers
- TN
3 papers · 3 as a fellow

2 papers

2 papers

2 papers
Grants
- 2025–2027
Fibroblast Activating Protein PET-CT Imaging of TB-Associated Fibrosis
National Institute of Allergy and Infectious Diseases · R21
PI · $446.9K · University of Pennsylvania
- 2023–2027
Regulation of eDHFR-Tagged Proteins with Trimethoprim PROTACs
National Institute of General Medical Sciences · R01
Contact PI · $2.4M · University of Pennsylvania
- 2024–2026
The Development of a GMP eDHFR Vector to Monitor Investigational CAR T Cell Therapies
National Institute of Allergy and Infectious Diseases · R41
PI · $300K · Vellum Biosciences Llc
- 2023–2025
Optimizing the Synthesis of[18F]FTMP for Commercial Distribution
National Institute of Biomedical Imaging and Bioengineering · R41
Contact PI · $299.9K · Vellum Biosciences Llc
Clinical trials
- 2026–2030
Fibroblast Activating Protein (FAP) PET/CT in Adults With Tuberculosis
Principal investigator · Recruiting · Early phase 1
University of Pennsylvania
- 2024–2027
FAPI-74 PET/CT in Adults With Fibrosis
Principal investigator · Recruiting · Phase 1
Abramson Cancer Center at Penn Medicine
- 2025–2027
Site PI · Recruiting · Phase 3
SOFIE
- 2025–2027
Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or Esophageal Cancer.
Site PI · Recruiting · Phase 3
SOFIE


