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Markey McNutt

Associate Professor at UT Southwestern Medical Center · Children's Health Andrews Institute

Credentials: · · · · · ·

History

Children's Health Andrews Institute
Present
University of Texas Southwestern Medical Center
Present
University of Texas Southwestern Medical Center
Present

Medical Genetics and Genomics
University of Texas Southwestern Medical Center
2015–2017
Endocrinology, Diabetes, and Metabolism
University of Texas Southwestern Medical Center
2013–2015
Internal Medicine
University of Texas Southwestern Medical Center
2011–2012
Univ of Texas Southwestern Med Sch at Dallas
2006–2010

Research

Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice
Journal of Clinical Investigation · 2006 · 587 citations
Molecular basis for LDL receptor recognition by PCSK9
Proceedings of the National Academy of Sciences of the United States of America · 2008 · 344 citations
Catalytic activity is not required for secreted PCSK9 to reduce low density lipoprotein receptors in HepG2 cells
Journal of Biological Chemistry · 2007 · First of 3 authors · 228 citations

Garrett Gotway
5 papers
Jay Horton
5 papers
Erika Vucko
3 papers
Gregory Enns
3 papers
JT
Janet Thomas
3 papers
LW
Leah Wessenberg
3 papers
Nicola Longo
3 papers
Ralph DeBerardinis
3 papers
Stephanie Sacharow
3 papers
Barbara Burton
2 papers
Can Ficicioglu
2 papers
CE
Caroline Eggerding
2 papers

Clinical trials

A Study to Evaluate Safety, Tolerability, and Efficacy of AB-1009 Gene Therapy (GAA Gene) in Adult Participants With Late-Onset Pompe Disease (PROGRESS-GT LOPD)
Site PI · Recruiting · Phase 1, Phase 2
AskBio Inc
2026–2032
A Study of JNT-517 in Participants With Phenylketonuria (PKU)
Site PI · Recruiting · Phase 3
Otsuka Pharmaceutical Development & Commercialization, Inc.
2025–2028
AAV Gene Therapy Clinical Study in Adult Classic PKU (PHEdom)
Site PI · Recruiting · Phase 1, Phase 2
NGGT INC.
2025–2030
Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers
Sub-investigator · Recruiting
University of Texas Southwestern Medical Center
2022–2027