Michael Kastan
Executive Director, Duke Cancer Institute · Duke University Hospital
Credentials: · · · ·
History
PresentDuke Cancer Institute Center · Duke University Hospital
- Present
- Present
Pediatrics
Research
Participation of p53 protein in the cellular response to DNA damage
Cancer Research · 1991 · First of 5 authors · 3,861 citations
Cell · 1992 · First of 9 authors · 3,174 citations
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
Nature · 2003 · 2,683 citations
12 papers
11 papers
- SG
5 papers · 2 as a fellow
4 papers
3 papers
3 papers · 3 as a resident
- SK
3 papers
- WN
3 papers
Grants
- 1997–2029
Cancer Center Support Grant (CCSG)
National Cancer Institute · P30
Contact PI · $92M · Duke University
- 2011–2022
The Role of ATM in Metabolic Stress Responses
National Cancer Institute · R01
Contact PI · $3.1M · Duke University
- 1992–2019
Cellular Stress Response Signaling Pathways
National Institute of Environmental Health Sciences · R01
Contact PI · $4.3M · Duke University
- 2011–2016
Chromatin Modulation Associated with DNA Breakage and Repair in Human Cells
National Cancer Institute · R01
Contact PI · $1.4M · Duke University