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Monique Evangeline Hinchcliff

Director of Clinical and Translational Research, Internal Medicine: Rheumatology · Yale School of Medicine

Credentials: · · · · ·

History

Yale School of Medicine
Present

Research

Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis
American Journal of Respiratory and Critical Care Medicine · 2019 · 1,022 citations
Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span
The Journal of Experimental Medicine · 2017 · 975 citations
Mycophenolate mofetil versus oral cyclophosphamide in scleroderma-related interstitial lung disease (SLS II): a randomised controlled, double-blind, parallel group trial
The Lancet Respiratory Medicine · 2016 · 831 citations

John Varga
59 papers
Dinesh Khanna
29 papers
Shervin Assassi
25 papers
Tracy Frech
24 papers
Robyn Domsic
23 papers
Virginia Steen
23 papers
Elana Bernstein
15 papers
Jessica Gordon
15 papers
Lorinda Chung
14 papers
Maureen Mayes
14 papers
Daniel Furst
13 papers
Faye Hant
11 papers

Grants

Validating Novel Outcomes to Enable Systemic Sclerosis Calcinosis Cutis Clinical Trials
National Institute of Arthritis and Musculoskeletal and Skin Diseases · R01
Contact PI · $486.7K · Yale University
2025–2028
Pathogenic Wnt-Beta Catenin Target Genes in Macrophages and Fibrosis
National Institute of Arthritis and Musculoskeletal and Skin Diseases · R01
Contact PI · $2.6M · Yale University
2019–2025
Molecular Biomarkers of Improvement for Patients with Systemic Sclerosis in an Open Label Trial of Mycophenolate Mofetil
National Institute of Arthritis and Musculoskeletal and Skin Diseases · R21
PI · $400.3K · Dartmouth College
2015–2018
Predictive Ability of Gene Expression Signatures In Skin as SSc Biomarkers
National Institute of Arthritis and Musculoskeletal and Skin Diseases · K23
Contact PI · $389.9K · Northwestern University
2013–2016

Clinical trials

Quantification of Calcinosis Cutis Disease Burden Using Computed Tomography Images
Principal investigator · Recruiting
Yale University
2025–2026
Rheumatology Patient Registry and Biorepository
Principal investigator · Recruiting
Yale University
2020–2030
Skin Biopsy Specimens as Biomarkers of Systemic Sclerosis and Response to Mycophenolate Mofetil
Principal investigator · Completed
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
2008–2011
RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis
Site PI · Recruiting · Phase 2, Phase 3
Cabaletta Bio
2024–2029