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Patricia J. Sime

Adjunct Professor - Department of Medicine, Pulmonary Diseases and Critical Care · URochester Medicine

Credentials: · · · ·

History

URochester Medicine
Present

UK-U Edinburgh Fac Med
1988
UK-U Edinburgh Fac Med
1984

Research

Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung
Journal of Clinical Investigation · 1997 · First of 5 authors · 866 citations
An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis
American Journal of Respiratory Cell and Molecular Biology · 2017 · 353 citations
Lactic acid is elevated in idiopathic pulmonary fibrosis and induces myofibroblast differentiation via pH-dependent activation of transforming growth factor-β
American Journal of Respiratory and Critical Care Medicine · 2012 · Last of 14 authors · 348 citations

Robert Kottmann
30 papers · 2 as a fellow
Fernando Martinez
8 papers
David Nagel
7 papers · 1 as a fellow
Keith Olsen
7 papers
Steven Feldon
7 papers
Toby Maher
7 papers
Anna Podolanczuk
6 papers
JR
Jesse Roman
6 papers
AP
Apostolos Perelas
5 papers
Haodong Xu
5 papers
Mark Utell
5 papers
Wonder Drake
5 papers

Grants

Novel Oral Small Molecules for Progressive Pulmonary Fibrosis
National Heart, Lung, and Blood Institute · R43
PI · $306.9K · Novomedix, Inc.
2024–2026
R01 Transfer from U. of Rochester- Lactate Promotes Scarring After Irradiation
National Heart, Lung, and Blood Institute · R01
Contact PI · $1.5M · Virginia Commonwealth University
2016–2022
Multidisciplinary Training in Pulmonary Research
National Heart, Lung, and Blood Institute · T32
Contact PI · $1.7M · University of Rochester
2001–2022
Novel Therapies for Cigarette Smoke Induced Lung Injury
National Heart, Lung, and Blood Institute · R01
Contact PI · $1.6M · University of Rochester
2014–2019