Patrick Lyden

Professor of Physiology and Neuroscience, Neurology, and Neurological Surgery. · University of Southern California/Los Angeles General Medical Center

Credentials: · · · · ·

History

Mechanisms and Treatment Implications of Differential Vulnerability in the Central Nervous System
National Institute of Neurological Disorders and Stroke · RF1
Contact PI · $1.2M · University of Southern California
2026–2029
The NIH SPAN Coordinating Center
National Institute of Neurological Disorders and Stroke · U24
Contact PI · $2.8M · University of Southern California
2023–2026
ZZ-3K3A-301: A Multicenter, Randomized, Placebo-Controlled, Double-Blinded, Phase 3 Study to Evaluate the Efficacy and Safety of 3K3A-APC (RHAPSODY-2)
National Institute of Neurological Disorders and Stroke · UG3
Contact PI · $4M · University of Southern California
2022–2024
The NIH SPAN Coordinating Center
National Institute of Neurological Disorders and Stroke · U24
Contact PI · $2.4M · University of Southern California
2019–2023

Efficacy and Safety Evaluation of 3K3A-APC in Ischemic Stroke
Principal investigator · Withdrawn · Phase 3
ZZ Biotech, LLC
2024–2026
Safety Evaluation of 3K3A-APC in Ischemic Stroke
Principal investigator · Completed · Phase 2
ZZ Biotech, LLC
2014–2017
Safety and Pharmacokinetics of Single and Multiple Ascending Doses of 3K3A-APC in Healthy Adult Volunteers
Principal investigator · Completed · Phase 1
ZZ Biotech, LLC
2012
The Intravascular Cooling in the Treatment of Stroke 2/3 Trial
Principal investigator · Terminated · Phase 2, Phase 3
University of California, San Diego
2010–2015