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Peter Sguigna

Assistant Professor · University of Texas Southwestern Medical Center

Credentials: · · ·

History

University of Texas Southwestern Medical Center
Present
Children's Health Andrews Institute
Present

Children's Health - Children's Medical Center of Dallas
2019–2020
Neurology
University of Texas Southwestern Medical Center
2014–2018
Univ of Texas Southwestern Med Sch at Dallas
2010–2014

Research

Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8
Proceedings of the National Academy of Sciences of the United States of America · 2011 · 141 citations
Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
Journal of Biological Chemistry · 2011 · 84 citations
Atypical Anti-MOG syndrome with aseptic meningoencephalitis and pseudotumor cerebri-like presentations
Case report · Multiple Sclerosis and Related Disorders · 2019 · 52 citations

Lauren Tardo
11 papers · 1 as a fellow
Benjamin Greenberg
9 papers
Kyle Blackburn
8 papers · 1 as a fellow
Olaf Stuve
8 papers
Darin Okuda
7 papers
Katy Burgess
7 papers
Lindsay Horton
6 papers
Crystal Wright
5 papers
Shanan Munoz
4 papers
Ethan Meltzer
3 papers · 2 as a fellow
KS
Kevin Shan
3 papers · 2 as a resident
Robert Hogan
3 papers

Clinical trials

Study of the Clinical and Radiological Impact of Ravulizumab in People With Neuromyelitis Optica Spectrum Disorder
Principal investigator · Recruiting
University of Texas Southwestern Medical Center
2024–2027
Study of Circadian Focused Light Therapy in Progressive Multiple Sclerosis
Principal investigator · Enrolling by invitation · Phase 1
University of Texas Southwestern Medical Center
2024–2026
31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Multiple Sclerosis.
Principal investigator · Completed · Phase 2
Clene Nanomedicine
2019–2025
Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)
Site PI · Recruiting · Phase 3
Mayo Clinic
2025–2031