Richard Hotchkiss
Physician · Washington University School of Medicine
Credentials: · ·
History
Research
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
JAMA · 2016 · 20,597 citations
The pathophysiology and treatment of sepsis
Review · New England Journal of Medicine · 2003 · First of 2 authors · Corresponding · 2,945 citations
Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy
Review · Nature reviews. Immunology · 2013 · First of 3 authors · 2,151 citations
45 papers
36 papers
28 papers · 1 as a resident
28 papers · 15 as a resident
28 papers
26 papers · 4 as a resident
23 papers
20 papers · 10 as a fellow
Grants
- 2018–2028
Enhancing Innate and Adaptive Immunity to Improve Sepsis Survival
National Institute of General Medical Sciences · R35
Contact PI · $4.7M · Washington University
- 1991–2018
Prevention of Apoptotic Cell Death in Sepsis by Bcl-2
National Institute of General Medical Sciences · R01
Contact PI · $5M · Washington University
- 2015–2018
Immunotherapy of Sepsis Using Anti-PDL1 Antibody
National Institute of General Medical Sciences · R34
PI · $158.4K · University of Pittsburgh at Pittsburgh
- 2012–2017
Mechanisms of Immunosuppression in Sepsis
National Institute of General Medical Sciences · R01
PI · $2.2M · Washington University
Clinical trials
- 2020–2022
Principal investigator · Terminated · Phase 2
Revimmune
- 2019–2021
Recombinant Interleukin-7 (CYT107) to Restore Absolute Lymphocyte Counts in Sepsis Patients
Principal investigator · Terminated · Phase 2
Revimmune
- 2016–2018
A Study of IL-7 to Restore Absolute Lymphocyte Counts in Sepsis Patients
Study director · Completed · Phase 2
Revimmune