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Robert Ferris

Lineberger Distinguished Professor Executive Director · University of North Carolina Hospitals

Credentials: · · · ·

History

Oncology Clinical Services UNC Health System Division · University of North Carolina Hospitals
Present
UNC Lineberger Comprehensive Cancer Center · University of North Carolina Hospitals
Present
UNC Health Division · University of North Carolina Hospitals
Present

Otolaryngology – Head and Neck Surgery
Johns Hopkins Hospital
1996–2001
Johns Hopkins School of Medicine
1991–1995

Research

Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck
New England Journal of Medicine · 2016 · First of 23 authors · 4,100 citations
Head and neck cancer
Review · The Lancet · 2008 · Last of 4 authors · 1,635 citations
The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction
Immunity · 2016 · 724 citations

Umamaheswar Duvvuri
80 papers · 1 as a resident
SK
Seungwon Kim
79 papers
JJ
Jonas Johnson
69 papers
Dwight Heron
53 papers
Raja Seethala
42 papers · 1 as a fellow
David Clump
35 papers · 5 as a resident
Jennifer Grandis
35 papers
JO
James Ohr
33 papers
Barton Branstetter
30 papers · 3 as a fellow
Dan Zandberg
29 papers
Julie Bauman
27 papers
Simion Chiosea
25 papers

Grants

Yale-UNC Head and Neck Cancer SPORE: Overcoming Treatment Resistance in Head and Neck Cancer
National Institute of Dental and Craniofacial Research · P50
PI · $1.8M · Yale University
2020–2031
Mechanistic Connection Between HPV-Specific TCRs and Therapeutic Responses to ICI in HPV+ HNSCC
National Cancer Institute · R01
PI · $2M · University of Pittsburgh at Pittsburgh
2024–2029
Mechanisms of PD-1 and Tim-3 Crosstalk in Tumor-Infiltrating Lymphocytes
National Cancer Institute · R01
Contact PI · $4.6M · University of Pittsburgh at Pittsburgh
2016–2028
Cancer Center Support Grant
National Cancer Institute · P30
Contact PI · $17M · Univ of North Carolina Chapel Hill
1997–2027

Clinical trials

Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer
Principal investigator · Completed · Phase 2
Robert L. Ferris, MD, PhD
2018–2024
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
Principal investigator · Recruiting · Phase 2
ECOG-ACRIN Cancer Research Group
2016–2027
Biological Vaccine: Semi-allogeneic Human Fibroblasts (MRC-5) Transfected With DNA
Principal investigator · Withdrawn · Phase 1
Robert Ferris
2016–2028
Safety Testing of Adding Nivolumab to Chemotherapy in Patients With Intermediate and High-Risk Local-Regionally Advanced Head and Neck Cancer
Principal investigator · Completed · Phase 1
RTOG Foundation, Inc.
2016–2022