
Sabrina Paganoni
Physician · Massachusetts General Hospital
Credentials: · · · · ·
History
- 2011–2012
Mass
- 2007–2008
- 1999–2000

- 1995–1999
Research
Muscle synergy patterns as physiological markers of motor cortical damage
Proceedings of the National Academy of Sciences of the United States of America · 2012 · 464 citations
Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis
New England Journal of Medicine · 2020 · First of 59 authors · 415 citations
Muscle & Nerve · 2011 · First of 5 authors · 246 citations

56 papers

54 papers

32 papers · 3 as a fellow

18 papers
- NA
18 papers
- DH
16 papers

16 papers
- NM
15 papers
Grants
- 2026–2030
National Institute of Neurological Disorders and Stroke · U01
Contact PI · $8.3M · Massachusetts General Hospital
- 2023–2028
Access for All in ALS (ALL ALS) East Clinical Coordinating Center
National Institute of Neurological Disorders and Stroke · OT2
PI · $71.5M · Massachusetts General Hospital
- 2023–2027
An Intermediate-Size Expanded Access Protocol for Amyotrophic Lateral Sclerosis with Pridopidine
National Institute of Neurological Disorders and Stroke · U01
Contact PI · $29.6M · Massachusetts General Hospital
- 2023–2027
National Institute of Neurological Disorders and Stroke · U01
PI · $33M · Massachusetts General Hospital
Clinical trials
- 2021–2022
A Phase 2 Study to Evaluate AL001 in C9orf72-Associated ALS
Principal investigator · Terminated · Phase 2
Alector Inc.
- 2018–2021
Open Label Extension Study of AMX0035 in Patients With ALS
Principal investigator · Completed · Phase 2
Amylyx Pharmaceuticals Inc.
- 2017–2020
Safety of Urate Elevation in Amyotrophic Lateral Sclerosis (ALS)
Principal investigator · Completed · Phase 2
Massachusetts General Hospital
- 2017–2019
AMX0035 in Patients With Amyotrophic Lateral Sclerosis (ALS)
Principal investigator · Completed · Phase 2
Amylyx Pharmaceuticals Inc.



