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Sana Karam

S. McDonnell III Distinguished Professor of Medicine, Chair, Department of Radiation Oncology · Washington University/B-JH/SLCH Consortium

Credentials: · · · · ·

History

Chair Department · Washington University/B-JH/SLCH Consortium
Present
Department of Radiation Oncology · Washington University/B-JH/SLCH Consortium
Present
Washington University/B-JH/SLCH Consortium
Present

Radiation Oncology
MedStar Health Georgetown University
2010–2014
Preliminary or Transitional Year
2009–2010
American University in Beirut, Beirut, Lebanon
Georgetown University School of Medicine
2005–2009
American University of Beirut

Research

Development and validation of a staging system for HPV-related oropharyngeal cancer by the International Collaboration on Oropharyngeal cancer Network for Staging (ICON-S): a…
The Lancet Oncology · 2016 · 582 citations
Resistance to Radiotherapy and PD-L1 Blockade Is Mediated by TIM-3 Upregulation and Regulatory T-Cell Infiltration
Clinical Cancer Research · 2018 · Last of 17 authors · Corresponding · 234 citations
Elective nodal irradiation mitigates local and systemic immunity generated by combination radiation and immunotherapy in head and neck tumors
Nature Communications · 2022 · Last of 20 authors · Corresponding · 201 citations

Arya Amini
35 papers · 16 as a resident
DR
David Raben
34 papers
Laurel Darragh
31 papers · 3 as a resident
Jessica McDermott
23 papers · 4 as a fellow
William Stokes
21 papers · 15 as a resident
AM
Adam Mueller
14 papers · 12 as a resident
Daniel Bowles
13 papers
Andy Phan
12 papers · 4 as a resident
Antonio Jimeno
12 papers
Brian Kavanagh
11 papers
Justin Yu
11 papers · 10 as a resident
Richard Ross
10 papers · 10 as a resident

Grants

Tackling Treg Mediated Resistance to Radiation and Anti-PDL1 in HNSCC's
National Institute of Dental and Craniofacial Research · R01
Contact PI · $3.7M · Washington University
2019–2029
Sexual Dimorphism and the Immuno-Modulatory Role of Estrogen Signaling in HNSCC
National Cancer Institute · R01
Contact PI · $2.6M · Washington University
2023–2028
Colorado Head and Neck Cancer SPORE
National Cancer Institute · P50
Project lead · $1.7M · University of Colorado Denver
2021–2027
Role of EphB4-Ephrin-B2 Interaction in Regulating Crosstalk Between Cancer Cell and Vascular Tumor Microenvironment in Head and Neck Cancer
National Institute of Dental and Craniofacial Research · R01
Contact PI · $2.4M · University of Colorado Denver
2019–2025

Clinical trials

Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)
Principal investigator · Not yet recruiting · Phase 1, Phase 2
Washington University School of Medicine
2026–2033
Radiotherapy in Combination With TTI-101 in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma
Principal investigator · Recruiting · Phase 1
Washington University School of Medicine
2024–2029
Radiotherapy in Combination With Atezolizumab Prior to Surgical Resection for HPV Unrelated HNSCC
Principal investigator · Completed · Phase 1
University of Colorado, Denver
2021–2024
Radiotherapy With Durvalumab Prior to Surgical Resection for HPV Negative Squamous Cell Carcinoma
Principal investigator · Completed · Phase 1
University of Colorado, Denver
2018–2023