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Sanaz Memarzadeh

Director, G.O. Discovery Laboratory, UCLA Broad Stem Cell Research Center · UCLA David Geffen School of Medicine/UCLA Medical Center

Credentials: · · · · ·

History

G.O. Discovery Laboratory · UCLA David Geffen School of Medicine/UCLA Medical Center
Present
UCLA David Geffen School of Medicine/UCLA Medical Center
Present
UCLA David Geffen School of Medicine/UCLA Medical Center
Present

Gynecologic Oncology
UCLA David Geffen School of Medicine/UCLA Medical Center
2000–2003
Obstetrics and Gynecology
UCLA David Geffen School of Medicine/UCLA Medical Center
1997–2000
University of Pittsburgh School of Medicine
1992–1996

Research

A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas
Cancer Cell · 2016 · 291 citations
Basal epithelial stem cells are efficient targets for prostate cancer initiation
Proceedings of the National Academy of Sciences of the United States of America · 2010 · 227 citations
Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation
Cell stem cell · 2010 · 222 citations

Neda Moatamed
15 papers
DP
Daniel Paik
5 papers · 5 as a resident
Jiaoti Huang
5 papers
Steven Raman
5 papers
Yuna Kang
5 papers
Ekaterina Tiourin
4 papers
Jonathan Berek
4 papers
NO
Nora Ostrzega
4 papers
Tiffany Lai
4 papers · 3 as a fellow
YZ
Yang Zong
4 papers
Amanda Schafenacker
3 papers
Beth Karlan
3 papers

Grants

Exploring Super Charged NK Cells as a Novel Cell-Based Immune Therapy in Targeting Platinum Resistant Ovarian Cancers
Department of Veterans Affairs · I01
Contact PI · Va Greater Los Angeles Healthcare System
2024–2029
Targeting Alternative Isoform Variation for TCR Discovery in Platinum-Resistant Ovarian Cancer
National Cancer Institute · R01
Contact PI · $2.1M · University of California Los Angeles
2024–2029
BCCMA: Overcoming Chemoresistance in Ovarian Cancer: Targeting Unique Vulnerabilities in Neuroendocrine-Like Ovarian Cancer Cells
Department of Veterans Affairs · I01
Contact PI · Va Greater Los Angeles Healthcare System
2023–2028
Reactivating p53 Function with a Novel Structure-Based Peptide as a Therapeutic Approach for Overcoming Platinum Resistance
Department of Veterans Affairs · I01
Contact PI · Va Greater Los Angeles Healthcare System
2020–2024

Clinical trials

Birinapant and Carboplatin in Treating Patients and Targeting Recurrent High Grade Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (HGSOC)
Principal investigator · Withdrawn · Phase 1, Phase 2
Jonsson Comprehensive Cancer Center
2018–2021