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Seth Karol

Associate Member, St. Jude Faculty · St Jude Children's Research Hospital

Credentials: · · · · ·

History

St Jude Children's Research Hospital
Present

Research

Venetoclax in combination with cytarabine with or without idarubicin in children with relapsed or refractory acute myeloid leukaemia: a phase 1, dose-escalation study
The Lancet Oncology · 2020 · First of 17 authors · 140 citations
NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells
Nature Genetics · 2015 · 140 citations
Clinical significance of novel subtypes of acute lymphoblastic leukemia in the context of minimal residual disease-directed therapy
Blood Cancer Discovery · 2021 · 134 citations

Ching-Hon Pui
62 papers
Hiroto Inaba
49 papers
Mary Relling
44 papers
Sima Jeha
39 papers
JR
Jeffrey Rubnitz
24 papers
Raul Ribeiro
18 papers
Mignon Loh
14 papers
Jeffery Klco
11 papers
Stephen Hunger
11 papers
Sue Kaste
11 papers
Elizabeth Raetz
10 papers
Eric Larsen
10 papers

Grants

Hypertension Intervention to Reduce Osteonecrosis in Children with Acute Lymphoblastic Leukemia
National Cancer Institute · K08
Contact PI · $1.1M · St. Jude Children's Research Hospital
2020–2025

Clinical trials

Real World Asparaginase Therapy Toxicity
Principal investigator · Not yet recruiting
St. Jude Children's Research Hospital
2026–2031
Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma
Principal investigator · Recruiting · Phase 2
St. Jude Children's Research Hospital
2025–2034
Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)
Principal investigator · Recruiting · Phase 2
St. Jude Children's Research Hospital
2024–2033
Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma
Principal investigator · Recruiting · Phase 4
St. Jude Children's Research Hospital
2024–2039